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Article
Open AccessSuccessful Use of Easyhaler® Dry Powder Inhaler in Patients with Chronic Obstructive Pulmonary Disease; Analysis of Peak Inspiratory Flow from Three Clinical Trials
There is increasing pressure to use environmentally friendly dry powder inhalers (DPI) instead of pressurized metered-dose inhalers (pMDI). However, correct inhalation technique is needed for effective inhale...
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Article
Open AccessFood hypersensitivity: an examination of factors influencing symptoms and temporal changes in the prevalence of sensitization in an adult sample
Food hypersensitivity (FHS) is common, but little is known about the factors associated with severe reactions, age of onset and whether sensitization persists. This study examines the factors associated with s...
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Article
Open AccessTraffic noise in the bedroom in association with markers of obesity: a cross-sectional study and mediation analysis of the respiratory health in Northern Europe cohort
Previous research suggests an association between road traffic noise and obesity, but current evidence is inconclusive. The aim of this study was to assess the association between nocturnal noise exposure and ...
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Article
Open AccessDiagnostic spirometry in COPD is increasing, a comparison of two Swedish cohorts
Spirometry should be used to confirm a diagnosis of chronic obstructive pulmonary disease (COPD). This test is not always performed, leading to possible misdiagnosis. We investigated whether the proportion of ...
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Article
Open AccessThe association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life: results from the Burden of Obstructive Lung Disease (BOLD) study
Spirometric small airways obstruction (SAO) is common in the general population. Whether spirometric SAO is associated with respiratory symptoms, cardiometabolic diseases, and quality of life (QoL) is unknown.
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Article
Open AccessCan we predict who will benefit most from biologics in severe asthma? A post-hoc analysis of two phase 3 trials
Individualized prediction of treatment response may improve the value proposition of advanced treatment options in severe asthma. This study aimed to investigate the combined capacity of patient characteristic...
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Article
Open AccessChronic Airways Assessment Test: psychometric properties in patients with asthma and/or COPD
No short patient-reported outcome (PRO) instruments assess overall health status across different obstructive lung diseases. Thus, the wording of the introduction to the Chronic Obstructive Pulmonary Disease (...
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Article
Open AccessHealth-related quality of life decreases in young people with asthma during the transition from adolescence to young adulthood: a birth cohort study
During the transition from paediatric to adult healthcare there is a gap between asthma guidelines and actual management with decreased healthcare consultations and dispensations of asthma medications after th...
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Article
Open AccessDoes multimorbidity result in de-prioritisation of COPD in primary care?
The aim of this study was to describe factors associated with having COPD regularly reviewed in primary care by a nurse or physician and assess whether there was de-prioritisation for COPD in multimorbid patie...
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Article
The effect of farming environment on asthma; time dependent or universal?
The increasing prevalence of asthma is linked to westernization and urbanization. Farm environments have been associated with a lower risk of asthma development. However, this may not be universal, as the asso...
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Article
Open AccessMAIT cell counts are associated with the risk of hospitalization in COPD
Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation associated with chronic inflammation in the airways. Mucosal-associated invariant T (MAIT) cells are unconventiona...
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Article
Open AccessEnvironmental Sustainability in Respiratory Care: An Overview of the healthCARe-Based envirONmental Cost of Treatment (CARBON) Programme
Faced with the challenges of climate change, countries are seeking to decarbonise their economies. A greater understanding of what comprises the carbon footprint of care in healthcare systems will identify pot...
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Article
Optimal communication associated with lower risk of acute traumatic stress after lung cancer diagnosis
The aim of this study was to assess the role of the patient’s background and perceived healthcare-related factors in symptoms of acute stress after lung cancer diagnosis.
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Article
Open AccessCOPD – do the right thing
A gap exists between guidelines and real-world clinical practice for the management and treatment of chronic obstructive pulmonary disease (COPD). Although this has narrowed in the last decade, there is room f...
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Article
Open AccessNasal symptoms increase the risk of snoring and snoring increases the risk of nasal symptoms. A longitudinal population study
Humans have a preference for nasal breathing during sleep. This 10-year prospective study aimed to determine if nasal symptoms can predict snoring and also if snoring can predict development of nasal symptoms....
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Article
Open AccessThe Association Between β-Dystroglycan in Airway Smooth Muscle and Eosinophils in Allergic Asthma
Allergic asthma (AA) is a complex disorder with heterogeneous features of airway hyperresponsiveness, inflammation, and remodeling. The increase of airway smooth muscle (ASM) mass is a fundamental component of...
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Article
Open AccessAssociation between lung function decline and obstructive sleep apnoea: the ALEC study
To study changes in lung function among individuals with a risk of obstructive sleep apnoea (OSA), and if asthma affected this relationship.
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Article
Open AccessCritical inhaler technique errors in Swedish patients with COPD: a cross-sectional study analysing video-recorded demonstrations
A correct use of inhaler devices is essential in chronic obstructive pulmonary disease (COPD) treatment. Critical errors were studied by analysing 659 video-recorded demonstrations of inhaler technique from 36...
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Article
Open AccessHealth impact assessment to predict the impact of tobacco price increases on COPD burden in Italy, England and Sweden
Raising tobacco prices effectively reduces smoking, the main risk factor for chronic obstructive pulmonary disease (COPD). Using the Health Impact Assessment tool “DYNAMO-HIA”, this study quantified the reduct...
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Article
Open AccessInhaled corticosteroids and the risk of type 2 diabetes among Swedish COPD patients
This study reports the association of ICS use and the risk of type 2 diabetes mellitus (T2DM) in Swedish patients with COPD using data from real-world, primary care settings. A total of 7078 patients with COPD...
