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  1. Article

    Open Access

    Distinct mechanical properties in homologous spectrin-like repeats of utrophin

    Patients with Duchenne muscular dystrophy (DMD) lack the protein dystrophin, which is a critical molecular component of the dystrophin-glycoprotein complex (DGC). Dystrophin is hypothesized to function as a mo...

    Sivaraman Rajaganapathy, Jackie L. McCourt, Sayan Ghosal… in Scientific Reports (2019)

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  2. No Access

    Chapter and Conference Paper

    Bridging Imaging, Genetics, and Diagnosis in a Coupled Low-Dimensional Framework

    We propose a joint dictionary learning framework that couples imaging and genetics data in a low dimensional subspace as guided by clinical diagnosis. We use a graph regularization penalty to simultaneously ca...

    Sayan Ghosal, Qiang Chen, Aaron L. Goldman… in Medical Image Computing and Computer Assis… (2019)