-
Article
Open AccessMucinous carcinoma originating from uterine adenomyosis: a case report
Uterine adenomyosis is rarely a precursor of malignant tumors, but the most frequent histological subtype is endometrioid carcinoma. We observed a rare case of mucinous carcinoma originating from uterine adeno...
-
Article
Open AccessInsufficient maternal gestational weight gain and infant neurodevelopment at 12 months of age: the Japan Environment and Children’s Study
Abnormal maternal gestational weight gain (GWG) increases the risk of obstetric-related complications. This investigation examined the impact of GWG on infant neurodevelopmental abnormalities at 12 months of a...
-
Article
Open AccessMaternal alcohol consumption and risk of offspring with congenital malformation: the Japan Environment and Children’s Study
The association between fetal exposure to alcohol and congenital structural disorders remains inconclusive. The present study searched for relationships between maternal alcohol consumption during pregnancy an...
-
Article
Association between pesticide usage during pregnancy and neonatal hyperbilirubinemia requiring treatment: the Japan Environment and Children’s Study
Maternal exposure to pesticides during pregnancy may cause oxidative hemolysis leading to neonatal hyperbilirubinemia. This investigation examined for associations between maternal use of pesticides or repelle...
-
Article
Open AccessPyosalpinx due to Cronobacter sakazakii in an elderly woman
Cronobacter sakazakii (C. sakazakii) is a bacterium known to cause severe neonatal infections in premature infants with the consumption of contaminated powdered milk formula. Adult infections are rare, and there ...
-
Article
Open AccessMaternal Exposure to Housing Renovation During Pregnancy and Risk of Offspring with Congenital Malformation: The Japan Environment and Children’s Study
There have been no large, nationwide, birth cohort studies in Japan examining the effects of house renovation during pregnancy on congenital abnormality. This study examined the impact of (1) prenatal exposure...
-
Article
Open AccessSawtooth fetal heart rate pattern associated with a favorable neurological outcome in an infant: a case report
The sawtooth fetal heart rate pattern is rare, and has been reported as a possible indicator of neurological sequelae in newborns. However, we observed this fetal heart rate pattern in an infant with normal ne...
-
Article
Open AccessAlcohol Consumption During Pregnancy and Risk of Placental Abnormality: The Japan Environment and Children’s Study
There have been no large nationwide birth cohort studies examining for the effects of maternal alcohol use during pregnancy on placental abnormality. This study searched for associations between alcohol consum...
-
Article
Histopathological findings of pregnancy-induced hypertension: histopathology of early-onset type reflects two-stage disorder theory
The placental tissues of pregnancy-induced hypertension (PIH) patients exhibit multiple infarctions, acute atherosis, distal villous hypoplasia, and increased syncytial knots. However, these findings are not o...
-
Article
Open AccessPrenatal sonographic diagnosis of fetal valproate syndrome: a case report
Prenatal exposure of mother to valproate (VPA) causes teratogenic effects in the fetus, namely fetal valproate syndrome (FVS). We report a case of fetal valproate syndrome rarely diagnosed by prenatal sonograp...
-
Article
Changes in the expression of E-cadherin repressors, Snail, Slug, SIP1, and Twist, in the development and progression of ovarian carcinoma: the important role of Snail in ovarian tumorigenesis and progression
Changes in the expression of E-cadherin have been reported to be important in the tumorigenesis and progression of epithelial ovarian carcinoma. To further examine the mechanisms regulating E-cadherin expressi...
-
Article
Quality control of Photosystem II under light stress – turnover of aggregates of the D1 protein in vivo
When photodamaged under excessive light, the D1 protein is digested and removed from Photosystem (PS) II to facilitate turnover of the protein. In vitro studies have shown that part of the photodamaged D1 protein...
-
Article
Levels of oxidative stress and redox-related molecules in the placenta in preeclampsia and fetal growth restriction
Recent evidence suggests that oxidative stress is involved in the pathophysiology of preeclampsia. Using immunohistochemistry and Western blotting, we investigated the oxidative stress- and redox-related molec...
-
Protocol
Assay of Photoinhibition of Photosystem II and Protease Activity
Under light-stress conditions, the photosystem (PS)II reaction center D1 protein is photodamaged. The damage to the D1 protein is induced by singlet oxygen molecules and endogenous free radicals generated by t...
