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Article
Open AccessA newly identified gene Ahed plays essential roles in murine haematopoiesis
The development of haematopoiesis involves the coordinated action of numerous genes, some of which are implicated in haematological malignancies. However, the biological function of many genes remains elusive ...
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Article
Open AccessQuantitative evaluation of corneal irregularity and scarring after infectious keratitis using anterior segment optical coherence tomography
Corneal scars after infectious keratitis lead to insufficient transparency and irregular astigmatism, affecting visual acuity; therefore, they should be accurately evaluated to estimate visual function. This s...
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Article
Open AccessCorneal irregularity and visual function using anterior segment optical coherence tomography in TGFBI corneal dystrophy
The purpose of this study was to evaluate corneal irregular astigmatism of patients with granular and lattice corneal dystrophy (GCD and LCD). 70 GCD, 35 LCD, and 81 control eyes were included. Anterior and po...
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Article
A Case of Irreversible Corneal Edema Associated with Dentatorubropallidoluysian Atrophy Following Corneal Endothelial Transplantation
Dentatorubropallidoluysian atrophy (DRPLA) is an autosomal dominant cerebellar ataxia with various signs and symptoms, including progressive ataxia, choreoathetosis, dementia, myoclonus, psychiatric problems, ...
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Article
Open AccessRisk factors and evaluation of keratoconus progression after penetrating keratoplasty with anterior segment optical coherence tomography
To determine the risk factors and unique characteristics of keratoconus (KC) progression after penetrating keratoplasty (PK), anterior segment optical coherence tomography parameters were statistically analyze...
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Article
Open AccessCorneal topography in keratoconus evaluated more than 30 years after penetrating keratoplasty: a Fourier harmonic analysis
The aim of this observational study was to examine the characteristics of anterior and posterior corneal topography in keratoconic eyes more than 30 years after penetrating keratoplasty (PK). Patients who main...
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Article
Open AccessAssociation of night eating habits with metabolic syndrome and its components: a longitudinal study
Night time eating is a risk factor for metabolic syndrome and obesity. The aim of this study was to investigate whether dinner immediately before bed, snacks after dinner, or combinations of both were associat...
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Article
Characteristics and risk factors of recurrent keratoconus over the long term after penetrating keratoplasty
To determine the characteristics and risk factors of recurrent keratoconus (KC) after penetrating keratoplasty (PK).
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Article
Open AccessChromatin states shape insertion profiles of the piggyBac, Tol2 and Slee** Beauty transposons and murine leukemia virus
DNA transposons and retroviruses are versatile tools in functional genomics and gene therapy. To facilitate their application, we conducted a genome-wide insertion site profiling of the piggyBac (PB), Tol2 and...
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Article
The impact of systemic vascular resistance on the accuracy of the FloTrac/Vigileo™ system in the perioperative period of cardiac surgery: a prospective observational comparison study
FloTrac/Vigileo™ system is based on arterial pressure waveform analysis arterial pressure-based CO (APCO). Therefore, systemic vascular resistance (SVR) can influence the accuracy of APCO. The purpose of this ...
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Article
A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening
This paper describes a method to enrich for homozygous mutant mouse embryonic stem cells without an inherently selectable phenotype. It is used to construct a bank of homozygous and heterozygous mutant cells a...
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Article
Changes in the expression of E-cadherin repressors, Snail, Slug, SIP1, and Twist, in the development and progression of ovarian carcinoma: the important role of Snail in ovarian tumorigenesis and progression
Changes in the expression of E-cadherin have been reported to be important in the tumorigenesis and progression of epithelial ovarian carcinoma. To further examine the mechanisms regulating E-cadherin expressi...
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Article
FARP2 triggers signals for Sema3A-mediated axonal repulsion
Sema3A, a prototypical semaphorin, acts as a chemorepellent or a chemoattractant for axons by activating a receptor complex comprising neuropilin-1 as the ligand-binding subunit and plexin-A1 as the signal-tra...
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Article
Long-term follow-up of diffuse membranoproliferative glomerulonephritis type I
In Japan, the school urinary screening system facilitates early detection and treatment of membranoproliferative glomerulonephritis (MPGN) in childhood. The present study investigated the long-term prognosis i...
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Article
Autoimmunity in chronic fatigue syndrome in children
We have reported that about half of children with chronic non-specific complaints were positive for antinuclear antibodies (ANA) and that the commonest complaint was fatigue in ANA-positive patients. Therefore...
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Article
Differential binding patterns of three antibodies (VOBM1, VOBM2, and VOM2) in the rat vomeronasal organ and accessory olfactory bulb
Immunohistochemical properties of monoclonal antibodies raised against the rat vomeronasal epithelium were examined in adult rats. Three monoclonal antibodies, VOBM1, VOBM2, and VOM2, reacted specifically to t...
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Chapter and Conference Paper
Immunocytochemical Study of the Vomeronasal Epithelium of the Infant Rat
The vomeronasal organ (VNO) is thought to be a detector of chemical signals, i.e., pheromones [1,2]. The primordium of the organ is first observed on embryonic day 11 and then gradually increases in size with ...
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Article
Antitumor action of an acidic glycoprotein (SAGP) fromStreptococcus pyogenes in mice
We have shown that an acidic glycoprotein (SAGP) isolated from a cell-free extract ofStreptococcus pyogenes (Su strain) prolonged the life-span of Ehrlich ascites carcinoma (EAC)bearing mice. The present study sh...
