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  1. Article

    Open Access

    Calcium-based phosphate binder use is associated with lower risk of osteoporosis in hemodialysis patients

    Loss of bone mineral density (BMD) is a substantial risk of mortality in addition to fracture in hemodialysis patients. However, the factors affecting BMD are not fully determined. We conducted a single-center...

    Hiroko Hashimoto, Satomi Shikuma, Shintaro Mandai, Susumu Adachi… in Scientific Reports (2021)

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  2. No Access

    Article

    Early response to erythropoiesis-stimulating agents in non-dialysis chronic kidney disease patients

    Renal anemia complicated with chronic kidney disease is usually treated with erythropoiesis-stimulating agents (ESAs). However, few studies have compared the early response of hemoglobin (Hb) to different kind...

    Michio Kuwahara, Youhei Arai, Eriko Takehara… in Clinical and Experimental Nephrology (2016)

  3. No Access

    Article

    Responsiveness to erythropoiesis-stimulating agents and renal survival in patients with chronic kidney disease

    Renal anemia of chronic kidney disease (CKD) is generally treated by erythropoiesis-stimulating agents (ESAs). However, there are individual differences in patients’ responsiveness to ESA, which may affect the...

    Michio Kuwahara, Shintaro Mandai, Yuri Kasagi… in Clinical and Experimental Nephrology (2015)

  4. No Access

    Article

    Effects of three kinds of erythropoiesis-stimulating agents on renal anemia in Japanese non-dialysis chronic kidney disease patients

    Erythropoiesis-stimulating agents (ESAs) are standard therapy for chronic kidney disease (CKD) patients with renal anemia. However, few studies have compared the effects of different ESAs on anemia in identica...

    Michio Kuwahara, Syoko Hasumi, Shintaro Mandai… in Clinical and Experimental Nephrology (2014)

  5. Article

    Open Access

    Lower serum sodium level predicts higher risk of infection-related hospitalization in maintenance hemodialysis patients: an observational cohort study

    Hyponatremia is associated with increased mortality in chronic kidney disease with and without end-stage renal disease (ESRD). Increasing evidence suggests that hyponatremia is not only a marker of severe unde...

    Shintaro Mandai, Michio Kuwahara, Yuri Kasagi, Keita Kusaka… in BMC Nephrology (2013)

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  6. No Access

    Article

    The impact of hyporesponsiveness to erythropoietin-stimulating agents on time-dependent mortality risk among CKD stage 5D patients: a single-center cohort study

    Hyporesponsiveness to a large dose of erythropoietin-stimulating agents (ESA) could increase mortality risk among chronic kidney disease patients. This study aimed to assess a safe dose of ESA and the impact o...

    Junichi Ishigami, Tsuyoshi Onishi, Satomi Shikuma… in Clinical and Experimental Nephrology (2013)

  7. No Access

    Article

    Effects of sevelamer hydrochloride on mortality, lipid abnormality and arterial stiffness in hemodialyzed patients: a propensity-matched observational study

    Cause-and-effect associations between sevelamer hydrochloride (HCl) and mortality have yet to be clarified. The effects of sevelamer HCl on mortality, lipid abnormality and arterial stiffness were examined in ...

    Soichiro Iimori, Yoshihiro Mori, Wataru Akita… in Clinical and Experimental Nephrology (2012)