35 Result(s)

Article

Testing on bacterial vaginosis in a subfertile population and time to pregnancy: a prospective cohort study

This study aimed to investigate the influence of bacterial vaginosis on time to pregnancy in subfertile couples.

Marjolein van den Tweel, Ellen van den Munckhof… in Archives of Gynecology and Obstetrics (2024)

Article

Hypertension and diabetes, but not leptin and adiponectin, mediate the relationship between body fat and chronic kidney disease

Obesity may promote kidney damage through hemodynamic and hormonal effects. We investigated the association between body mass index (BMI), total body fat (TBF) and chronic kidney disease (CKD) and whether hype...

Robin Lengton, Friedo W. Dekker, Elisabeth F. C. van Rossum… in Endocrine (2024)

Article

Influence of initial misdiagnosis on mortality in patients with bacteraemia: propensity score matching and propensity score weighting analyses

The diagnostic process is a key element of medicine but it is complex and prone to errors. Infectious diseases are one of the three categories of diseases in which diagnostic errors can be most harmful to pati...

Anna M. Eikenboom, Merel M. C. Lambregts, Mark G. J. de Boer… in BMC Infectious Diseases (2024)

Article

Risk of recurrence after local resection of T1 rectal cancer: a meta-analysis with meta-regression

T1 rectal cancer (RC) patients are increasingly being treated by local resection alone but uniform surveillance strategies thereafter are lacking. To determine whether different local resection techniques infl...

Nik Dekkers, Hao Dang, Jolein van der Kraan, Saskia le Cessie… in Surgical Endoscopy (2022)

Article

Systemic inflammatory markers in relation to cognitive function and measures of brain atrophy: a Mendelian randomization study

Observational studies have implied associations between multiple cytokines and cognitive decline, anti-inflammatory drugs however did not yield any protective effects on cognitive decline. We aimed to assess t...

Jiao Luo, Saskia le Cessie, Gerard Jan Blauw, Claudio Franceschi… in GeroScience (2022)

Article

Flemish population-based cancer screening programs: impact of COVID-19 related shutdown on short-term key performance indicators

Many breast, colorectal, and cervical cancer screening programs were disrupted due to the COVID-19 pandemic. This study aimed to estimate the short-term impact of the temporary shutdown (from March until May- ...

Svetlana Jidkova, Sarah Hoeck, Eliane Kellen, Saskia le Cessie… in BMC Cancer (2022)

Article

Coronavirus disease 2019 and peripheral blood eosinophil counts: a retrospective study

Eosinopenia has been described in COVID-19. With this study, we aim to study the peripheral blood eosinophil counts in COVID-19 patients and to investigate whether there is an association between the periphera...

Marjella Eijmael, Nicky Janssens, Saskia le Cessie, Yordi van Dooren… in Infection (2021)

Article

The PRolaCT studies — a study protocol for a combined randomised clinical trial and observational cohort study design in prolactinoma

First-line treatment for prolactinomas is a medical treatment with dopamine agonists (DAs), which effectively control hyperprolactinaemia in most patients, although post-withdrawal remission rates are approxim...

Ingrid M. Zandbergen, Amir H. Zamanipoor Najafabadi, Iris C. M. Pelsma… in Trials (2021)

Article

Prediction meets causal inference: the role of treatment in clinical prediction models

In this paper we study approaches for dealing with treatment when develo** a clinical prediction model. Analogous to the estimand framework recently proposed by the European Medicines Agency for clinical tri...

Nan van Geloven, Sonja A. Swanson, Chava L. Ramspek… in European Journal of Epidemiology (2020)

Article

Hidden analyses: a review of reporting practice and recommendations for more transparent reporting of initial data analyses

In the data pipeline from the data collection process to the planned statistical analyses, initial data analysis (IDA) typically takes place between the end of the data collection and do not touch the research...

Marianne Huebner, Werner Vach, Saskia le Cessie… in BMC Medical Research Methodology (2020)

Article

Authors’ Reply: A comparison of different methods to handle missing data in the context of propensity score analysis

Jungyeon Choi, Olaf M. Dekkers, Saskia le Cessie in European Journal of Epidemiology (2020)

Article

Metabolomics: a search for biomarkers of visceral fat and liver fat content

Excess visceral and liver fat are known risk factors for cardiometabolic disorders. Metabolomics might allow for easier quantification of these ectopic fat depots, instead of using invasive and costly tools su...

Sebastiaan Boone, Dennis Mook-Kanamori, Frits Rosendaal, Martin den Heijer… in Metabolomics (2019)

Article

Risk of Clinically Relevant Pericardial Effusion After Pediatric Cardiac Surgery

Pericardial effusion (PE) after pediatric cardiac surgery is common. Because of the lack of a uniform classification of the presence and severity of PE, we evaluated PE altering clinical management: clinically...

Rik Adrichem, Saskia Le Cessie, Mark G. Hazekamp… in Pediatric Cardiology (2019)

Article

A comparison of different methods to handle missing data in the context of propensity score analysis

Propensity score analysis is a popular method to control for confounding in observational studies. A challenge in propensity methods is missing values in confounders. Several strategies for handling missing va...

Jungyeon Choi, Olaf M. Dekkers, Saskia le Cessie in European Journal of Epidemiology (2019)

Article

Postprandial metabolite profiles associated with type 2 diabetes clearly stratify individuals with impaired fasting glucose

Fasting metabolite profiles have been shown to distinguish type 2 diabetes (T2D) patients from normal glucose tolerance (NGT) individuals.

Ruifang Li-Gao, Renée de Mutsert, Patrick C. N. Rensen… in Metabolomics (2017)

Article

Pulmonary function, exhaled nitric oxide and symptoms in asthma patients with obesity: a cross-sectional study

Obesity is a risk factor for the development of asthma. In patients with obesity the diagnosis of asthma is often based on symptoms, but without objective measurements. Nevertheless, obesity-associated asthma ...

Marise J. Kasteleyn, Tobias N. Bonten, Renée de Mutsert… in Respiratory Research (2017)