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Article
Open AccessDiscovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension
Hypertension remains a leading cause of cardiovascular and kidney diseases. Failure to control blood pressure with ≥ 3 medications or control requiring ≥ 4 medications is classified as resistant hypertension (...
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Article
Open AccessHysterectomy and women’s health in India: evidence from a nationally representative, cross-sectional survey of older women
Hysterectomy, particularly when conducted in women younger than 45 years, has been associated with increased risk of non-communicable diseases. In India, research indicates that hysterectomy is a common proced...
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Article
Laparoscopic Sleeve Gastrectomy in Patients with Obesity and Ventricular Assist Devices: a Comprehensive Outcome Analysis
We analyzed in detail the outcomes of eight patients with ventricular assist devices (VADs) and obesity who underwent laparoscopic sleeve gastrectomy (LSG) at a single heart transplant (HT) center. This compre...
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Article
Open AccessLaparoscopic sleeve gastrectomy in obese patients with ventricular assist devices: a data note
Patients with end-stage heart failure (ESHF) treated with ventricular assist devices (VADs) tend to gain weight after implantation, which is associated with higher complication rates and is a contraindication ...
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Article
Open AccessServices for women’s sexual and reproductive health in India: an analysis of treatment-seeking for symptoms of reproductive tract infections in a nationally representative survey
Women’s health policy in India has had a longstanding focus on maternal health and family planning. Recent policy highlights the importance of expanding women’s access to a broader range of sexual and reproduc...
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Article
Open AccessAuthor Correction: G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessG Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody
The experimental evidence that Adhesion G Protein-Coupled Receptors (aGPCRs) functionally couple to heterotrimeric G proteins has been emerging in incremental steps, but attributing biological significance to ...
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Article
Open AccessIn search of a small molecule agonist of the relaxin receptor RXFP1 for the treatment of liver fibrosis
The peptide hormone human relaxin-2 (H2-RLX) has emerged as a potential therapy for cardiovascular and fibrotic diseases, but its short in vivo half-life is an obstacle to long-term administration. The discovery ...
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Scaling-Up a Community-Based Approach to SDH: Reflections on the SEWA Experience
The Self Employed Women’s Association (SEWA), an organization of women workers across India, addresses the social determinants of health (SDH) in practice, through a community-based approach led by health work...
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Article
Open AccessUnderstanding CBHI hospitalisation patterns: a comparison of insured and uninsured women in Gujarat, India
Community-based health insurance has been associated with increased hospitalisation in low-income settings, but with limited analysis of the illnesses for which claims are submitted. A review of claims submitt...
