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    A single-molecule dissection of ligand binding to a protein with intrinsic dynamics

    Proteins that sample multiple conformations in the absence of a ligand have been presumed to operate via a conformational selection mechanism. Single molecule FRET studies of maltose binding protein now cast d...

    Eunkyung Kim, Sanghwa Lee, Aram Jeon, Jung Min Choi… in Nature Chemical Biology (2013)