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Open AccessThe association of arterial partial oxygen pressure with mortality in critically ill sepsis patients: a nationwide observational cohort study
Although several trials were conducted to optimize the oxygenation range in intensive care unit (ICU) patients, no studies have yet reached a universal recommendation on the optimal a partial pressure of oxyge...
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Open AccessPrognosis of mechanically ventilated patients with COVID-19 after failure of high-flow nasal cannula: a retrospective cohort study
There is an argument whether the delayed intubation aggravate the respiratory failure in Acute respiratory distress syndrome (ARDS) patients with coronavirus disease 2019 (COVID-19). We aimed to investigate th...
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Open AccessClinical impact of pre-existing acute exacerbation in patients with interstitial lung disease who underwent lung transplantation
Acute exacerbation of interstitial lung disease (AE-ILD) significantly impacts prognosis, leading to high mortality rates. Although lung transplantation is a life-saving treatment for selected patients with IL...
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Article
Open AccessImpact of a cumulative positive fluid balance during the first three ICU days in patients with sepsis: a propensity score-matched cohort study
The optimal strategy for fluid management during the first few days of ICU in sepsis patients remains controversial. We aimed to investigate the impact of cumulative fluid balance during the first three days o...
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Article
Fabrication of a Liquid Scintillator based on 7-Diethylamino-4-Methylcoumarin for Radiation Detection
Organic liquid scintillation detectors are widely used to measure the presence of radiation. With these devices, there are advantages in that they are easy to manufacture, large in size, and have a short fluor...
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Article
Open AccessComparison of the end-of-life decisions of patients with hospital-acquired pneumonia after the enforcement of the life-sustaining treatment decision act in Korea
Although the Life-Sustaining Treatment (LST) Decision Act was enforced in 2018 in Korea, data on whether it is well established in actual clinical settings are limited. Hospital-acquired pneumonia (HAP) is a c...
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Article
Open AccessA targeted metabolomics approach for sepsis-induced ARDS and its subphenotypes
Acute respiratory distress syndrome (ARDS) is etiologically and clinically a heterogeneous disease. Its diagnostic characteristics and subtype classification, and the application of these features to treatment...
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Article
Open AccessIncidence, risk factors, and clinical characteristics of airway complications after lung transplantation
Airway complications may occur after lung transplantation and are associated with considerable morbidity and mortality. We investigated the incidence, risk factors, and clinical characteristics of these compli...
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Article
Open AccessMortality of patients with hospital-onset sepsis in hospitals with all-day and non-all-day rapid response teams: a prospective nationwide multicenter cohort study
Hospital-onset sepsis is associated with a higher in-hospital mortality rate than community-onset sepsis. Many hospitals have implemented rapid response teams (RRTs) for early detection and timely management o...
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Article
Open AccessImpact of nutrition and physical activity on outcomes of hospital-acquired pneumonia
Frailty is an important risk factor for adverse health-related outcomes. It is classified into several phenotypes according to nutritional state and physical activity. In this context, we investigated whether ...
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Article
Open AccessPrognostic implication of bronchoalveolar lavage fluid analysis in patients with Pneumocystis jirovecii pneumonia without human immunodeficiency virus infection
The prognostic value of bronchoalveolar lavage (BAL) fluid analysis in non-human immunodeficiency virus (HIV)-infected patients with Pneumocystis jirovecii pneumonia (PJP) has not been well elucidated. We aimed t...
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Article
Fast neutron-gamma discrimination in organic scintillators via convolution neural network
Due to the high gamma sensitivity of organic scintillators, it is essential to discriminate signals induced by neutron from gamma-ray in fast-neutron detection. With the improvement of digital signal processin...
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Article
Open AccessThe feasibility of extracorporeal cardiopulmonary resuscitation for patients with active cancer who undergo in-hospital cardiac arrest
Indications of extracorporeal cardiopulmonary resuscitation (ECPR) are still debatable, particularly in patients with cancer. Prediction of the prognosis of in-hospital cardiac arrest (IHCA) in patients with c...
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Open AccessRelationship between the presence of dedicated doctors in rapid response systems and patient outcome: a multicenter retrospective cohort study
Rapid response systems (RRSs) improve patients’ safety, but the role of dedicated doctors within these systems remains controversial. We aimed to evaluate patient survival rates and differences in types of int...
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Article
Open AccessPredictive value of pre-arrest albumin level with GO-FAR score in patients with in-hospital cardiac arrest
We investigated whether combining the pre-arrest serum albumin level could improve the performance of the Good Outcome Following Attempted Resuscitation (GO-FAR) score for predicting neurologic outcomes in in-...
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Article
Open AccessThe association between hospital length of stay before rapid response system activation and clinical outcomes: a retrospective multicenter cohort study
Rapid response system (RRS) is being increasingly adopted to improve patient safety in hospitals worldwide. However, predictors of survival outcome after RRS activation because of unexpected clinical deteriora...
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Article
Open AccessClinical outcomes according to cannula configurations in patients with acute respiratory distress syndrome under veno-venous extracorporeal membrane oxygenation: a Korean multicenter study
Recirculation during veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a known drawback that limits sufficient oxygenation. This study aimed to compare the short-term oxygenation and long-term morta...
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Article
Open AccessEffect of High-dose Antithrombin Supplementation in Patients with Septic Shock and Disseminated Intravascular Coagulation
The efficacy of antithrombin (AT) administration in patients with septic shock and disseminated intravascular coagulation (DIC) was uncertain. This study aimed to investigate whether high-dose AT administratio...
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Article
Effect of adjunctive corticosteroid on 28-day mortality in neutropenic patients with septic shock
The role of adjunctive corticosteroid in septic shock remains debatable, and its role has not been assessed in neutropenic patients. We evaluated whether hydrocortisone reduces 28-day mortality in neutropenic ...
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Open AccessSerum developmental endothelial locus-1 is associated with severity of sepsis in animals and humans
Disruption of the endothelial glycocalyx has a prominent role in the pathophysiology of sepsis. Developmental endothelial locus-1 (Del-1) is an endothelial-derived anti-inflammatory factor. We hypothesized tha...
