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Article
Open AccessPotential biomarkers for neuroinflammation and neurodegeneration at short and long term after neonatal hypoxic-ischemic insult in rat
Hypoxic-ischemic (HI) encephalopathy causes life-long morbidity and premature mortality in term neonates. Therapies in addition to whole-body cooling are under development to treat the neonate at risk for HI e...
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Open AccessErratum: REAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer’s disease mouse model
Scientific Reports 6: Article number: 35719; published online: 24 October 2016; updated: 18 November 2016.
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Article
Open AccessREAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer’s disease mouse model
The search for new therapeutic approaches to Alzheimer disease (AD) is a major goal in medicine and society, also due to the impressive economic and social costs of this disease. In this scenario, biotechnolog...
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Article
Open AccessMulti-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice
Alzheimer disease is a multifactorial disorder characterized by the progressive deterioration of neuronal networks. The pathological hallmarks includes extracellular amyloid plaques and intraneuronal neurofibr...
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Article
Open AccessGender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis
Multiple sclerosis (MS) varies considerably in its incidence and progression in females and males. In spite of clinical evidence, relatively few studies have explored molecular mechanisms possibly involved in ...
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Article
Open AccessIntravitreal NGF administration counteracts retina degeneration after permanent carotid artery occlusion in rat
The neurotrophin nerve growth factor (NGF) is produced by different cell types in the anterior and posterior eye, exerting a neuroprotective role in the adult life. The visual system is highly sensitive to NGF...
