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Article
Bioaccumulation of Chloropyrifos Organo-pesticide and Its Toxicogenic Association with Antioxidant GSTP1 in Pakistani Pest Control Workers
Synthetic pesticides are employed to enhance agricultural production. Chronic exposure to organophosphate (OP) pesticides may be a source of health problems. The present study was designed to examine an associ...
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Article
Open AccessMutations in PGRN gene associated with the risk of psoriasis in Pakistan: a case control study
Psoriasis is a chronic, autoimmune, papulosquamous skin disorder, characterized by the formation of drop-like papules and silvery-white plaques surrounded by reddened or inflamed skin, existing predominantly o...
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Chapter and Conference Paper
USE-Based Deep Learning Approach to Detect Spammers on Twitter
Spammers disseminating obscene content on Twitter have been studied and detected using various hybrid features and machine learning approaches in past. To have greater insight into data prevailing in form of t...
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Chapter
Big Data in Smart Ecosystems: Trends, Challenges and Future Prospectus
Technology is transmuting the world. The rapid use of mobile devices and explosion of social media has given rise to the storm that is engulfing the world with data. Due to independent and excessive use of tec...
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Article
Open AccessInsights of OPs and PYR cytotoxic potential Invitro and genotoxic impact on PON1 genetic variant among exposed workers in Pakistan
Different pesticide chemicals are used to enhance crop yield by protecting from pests. Organophosphate (OPs) and Pyrethroid (PYR) are used in fields of Sanghar, Sindh Pakistan. PON1 an antioxidant enzyme impli...
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Chapter and Conference Paper
Emergent Use of Artificial Intelligence and Social Media for Disaster Management
Timely access to up-to-date and relevant disaster information is crucial for disaster response organizations to make effective decisions and proper management strategies to lessen the impact of disasters. In r...
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Article
Association of genetic polymorphism rs2071676 in carbonic anhydrase gene (CA9) with the risk of squamous cell carcinoma of lungs and esophagus
Esophageal and lung Squamous Cell Carcinoma (SCC) pose a serious threat to health as they are amongst the most prevalent cancers in Pakistan. Increased metabolic and energy needs within the proliferating cance...
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Article
Pyrethroid exposure: as determinant of CYP1A1 and GSTP1 genetic variations in occupationally exposed Sindh farmers
Pyrethroid (PYR) is a class of pesticide which was frequently applied in agricultural fields of Sanghar in Pakistan. Consistent and over use of PYR may lead to health effects on workers who are occupationally ...
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Article
Association analysis and allelic distribution of deletion in CC chemokine receptor 5 gene (CCR5Δ32) among breast cancer patients of Pakistan
Chemokine CC receptor type 5 (CCR5) is a cell surface receptor that has high affinity for chemotropic cytokines called chemokines. The CCR5 gene contains a 32 base pairs (bp) deletion (CCR5Δ32). This deletion may...
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Article
Open AccessSLC11A1 polymorphisms and host susceptibility to cutaneous leishmaniasis in Pakistan
The vector-borne cutaneous leishmaniasis (CL) is endemic in several regions of Pakistan mainly affecting poor populations. Host genetic factors, particularly SLC11A1 (solute carrier transmembrane protein) within ...
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Article
The association of GSTM1 and GSTT1 polymorphisms with squamous cell carcinoma of cervix in Pakistan
Gene deletions in GSTM1 and GSTT1 may result in tempering the activation and detoxification of several carcinogens and thereby may increase the risk of cancer pre-disposition. This study aims to investigate th...
