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Article
Open AccessDifferential analysis of histopathological and genetic markers of cancer aggressiveness, and survival difference in EBV-positive and EBV-negative prostate carcinoma
Several studies have shown an association between prostate carcinoma (PCa) and Epstein-Barr virus (EBV); however, none of the studies so far have identified the histopathological and genetic markers of cancer ...
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Article
Synthesis of coal-biomass blended fuel through coal-wet briquetting technology
Recent years have seen a substantial increase in interest in using biomass as a renewable energy source due to concerns about sustainability and energy security. However, using biomass alone as a fuel source h...
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Article
Open AccessHow Does Sustainable Management Practices Affect Weed Flora and Tuber Yield of Potato Crop in Mediterranean Environment?
Intensive potato cultivation affects weed species composition by selecting dominant and competitive weeds that represent a constraint of potato productivity. Field experiments were conducted during 2015 and 20...
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Article
Open AccessAcidified manure and nitrogen-enriched biochar showed short-term agronomic benefits on cotton–wheat crop** systems under alkaline arid field conditions
Application of organic residues such as farm manure and biochar in various agricultural environments have shown positive effects on soil carbon sequestration. However, there is a lack of consensus regarding th...
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Article
Strigolactone-Mediated Oxidative Stress Alleviation in Brassica rapa Through Upregulating Antioxidant System Under Water Deficit Conditions
Plant’s sensitivity to abiotic stresses such as extreme temperature, salinity, and drought threatens crop productivity worldwide. Here, the water deficit-induced response of Brassica rapa was modulated by the app...
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Article
Open AccessBiochar Amendment in Combination with Endophytic Bacteria Stimulates Photosynthetic Activity and Antioxidant Enzymes to Improve Soybean Yield Under Drought Stress
The beneficial effects of biochar (BC) and plant growth-promoting bacteria (PGPR) to increase crop yields under harsh environments have been widely reported. However, the knowledge on the synergistic effects o...
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Article
Predicting the efficiency of bare silica-based nano-fluid flooding in sandstone reservoirs for enhanced oil recovery through machine learning techniques using experimental data
Determining additional oil recovery from a silica nano-fluid enhanced oil recovery project is essential prior to its field scale application to prepare economic feasibility of the project. Measurement of oil r...
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Article
Open AccessDetection and characterization of latency stage of EBV and histopathological analysis of prostatic adenocarcinoma tissues
The pathophysiology of prostate cancer involves both genetic and acquired factors, including pathogens, such as viruses. A limited number of studies have shown the presence of Epstein-Barr virus (EBV) in prost...
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Article
Open AccessSpectrum of germline pathogenic variants using a targeted next generation sequencing panel and genotype-phenotype correlations in patients with suspected hereditary breast cancer at an academic medical centre in Pakistan
Breast cancer is the most common malignancy in women, affecting over 1.5 million women every year, which accounts for the highest number of cancer-related deaths in women globally.
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Article
Open AccessBiochar and slow-releasing nitrogen fertilizers improved growth, nitrogen use, yield, and fiber quality of cotton under arid climatic conditions
The efficiency of nitrogenous fertilizers in South Asia is on a declining trajectory due to increased losses. Biochar (BC) and slow-releasing nitrogen fertilizers (SRNF) have been found to improve nitrogen use...
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Chapter
Mulching Effects on Soil Greenhouse Gas Emission in Agricultural Systems
Agricultural activities are among the most important sources of atmospheric GHGs that are the primary causes of adverse climate changes. Therefore, efforts must be made to reduce GHGs source capacities of diff...
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Article
Open AccessAtypical involvement of central nervous system in classic Hodgkin lymphoma: a case report
Hodgkin lymphoma is a systemic disease that commonly involves the cervical, supraclavicular, and mediastinal lymph nodes. The involvement of central nervous system in Hodgkin lymphoma is extremely rare, and di...
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Article
Association of genetic polymorphism rs2071676 in carbonic anhydrase gene (CA9) with the risk of squamous cell carcinoma of lungs and esophagus
Esophageal and lung Squamous Cell Carcinoma (SCC) pose a serious threat to health as they are amongst the most prevalent cancers in Pakistan. Increased metabolic and energy needs within the proliferating cance...
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Article
Open AccessMineral nitrogen captured in field-aged biochar is plant-available
Biochar may serve as a tool to sustainably mitigate climate change via carbon sequestration and by improving soil fertility. Biochar has shown to retain nitrate in its pores, which increases with an organic co...
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Chapter
Modern Concepts and Techniques for Better Cotton Production
Sustainable cotton production in current environmental conditions is under threat due to climatic variability and shortage of ever-decreasing resources for agricultural crops. There is dire need to improve the...
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Chapter
Climate Resilient Cotton Production System: A Case Study in Pakistan
Cotton production is most vulnerable to climate change particularly in Pakistan, and sustainable cotton yield is critical to accomplish the future demand of the country. Climate change has negative impact on c...
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Article
Different nitrogen and biochar sources’ application in an alkaline calcareous soil improved the maize yield and soil nitrogen retention
We investigated effect of biochars (BCs) and nitrogen (N) fertilizers on soil selected characteristics, growth of maize, and soil N transformations in a pot experiment. Maize was grown in soil amended with con...
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Article
Association analysis and allelic distribution of deletion in CC chemokine receptor 5 gene (CCR5Δ32) among breast cancer patients of Pakistan
Chemokine CC receptor type 5 (CCR5) is a cell surface receptor that has high affinity for chemotropic cytokines called chemokines. The CCR5 gene contains a 32 base pairs (bp) deletion (CCR5Δ32). This deletion may...
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Article
Biochar but not humic acid product amendment affected maize yields via improving plant-soil moisture relations
Biochar (BC) and humic acid product (HAP) soil amendments may improve plant performance under water-limited conditions. Our aim was to investigate if BC and HAP amendments, alone or in combination, will have p...
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Article
The association of GSTM1 and GSTT1 polymorphisms with squamous cell carcinoma of cervix in Pakistan
Gene deletions in GSTM1 and GSTT1 may result in tempering the activation and detoxification of several carcinogens and thereby may increase the risk of cancer pre-disposition. This study aims to investigate th...