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  1. No Access

    Article

    A microfluidic cell-migration assay for the prediction of progression-free survival and recurrence time of patients with glioblastoma

    Clinical scores, molecular markers and cellular phenotypes have been used to predict the clinical outcomes of patients with glioblastoma. However, their clinical use has been hampered by confounders such as pa...

    Bin Sheng Wong, Sagar R. Shah, Christopher L. Yankaskas… in Nature Biomedical Engineering (2021)

  2. No Access

    Article

    A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm

    In asthma, the contraction of the airway smooth muscle and the subsequent decrease in airflow involve a poorly understood set of mechanical and biochemical events. Organ-level and molecular-scale models of the...

    Onur Kilic, Arum Yoon, Sagar R. Shah, Hwan Mee Yong… in Nature Biomedical Engineering (2019)