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  1. No Access

    Article

    A microfluidic cell-migration assay for the prediction of progression-free survival and recurrence time of patients with glioblastoma

    Clinical scores, molecular markers and cellular phenotypes have been used to predict the clinical outcomes of patients with glioblastoma. However, their clinical use has been hampered by confounders such as pa...

    Bin Sheng Wong, Sagar R. Shah, Christopher L. Yankaskas… in Nature Biomedical Engineering (2021)

  2. No Access

    Article

    A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm

    In asthma, the contraction of the airway smooth muscle and the subsequent decrease in airflow involve a poorly understood set of mechanical and biochemical events. Organ-level and molecular-scale models of the...

    Onur Kilic, Arum Yoon, Sagar R. Shah, Hwan Mee Yong… in Nature Biomedical Engineering (2019)

  3. Article

    Open Access

    Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases

    Collective cell migration occurs in many patho-physiological states, including wound healing and invasive cancer growth. The integrity of the expanding epithelial sheets depends on extracellular cues, includin...

    **Seok Park, Deok-Ho Kim, Sagar R. Shah, Hong-Nam Kim, Kshitiz… in Nature Communications (2019)

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  4. No Access

    Article

    Heterozygous IDH1R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP

    Mutations in the isocitrate dehydrogenase 1 (IDH1) gene have been identified in a number of cancer types, including brain cancer. The Cancer Genome Atlas project has revealed that IDH1 mutations occur in 70–80% o...

    Shuang Wei, Jie Wang, Olutobi Oyinlade, Ding Ma, Shuyan Wang, Lisa Kratz… in Oncogene (2018)

  5. Article

    Erratum to: PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment

    Dimitrios Mathios, Jacob Ruzevick, Christopher M. Jackson… in Journal of Neuro-Oncology (2016)

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  6. No Access

    Article

    Surgical management of Skene’s gland abscess/infection: a contemporary series

    We report our experience with surgical excision for treatment of Skene’s gland abscess/infection after conservative measures have failed.

    Sagar R. Shah, Grace Y. Biggs, Nirit Rosenblum… in International Urogynecology Journal (2012)

  7. No Access

    Chapter

    Robotic Transperitoneal Four Arm Laparoscopic Radical Prostatectomy: Points of Technique

    Sagar R. Shah, Vipul R. Patel in Urologic Robotic Surgery (2008)