34 Result(s)

Article

Human genome meeting 2016

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder

A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard… in Human Genomics (2016)

Article

Decision analysis for donor selection in stem cell transplantation—HLA-8/8 allele-matched unrelated donor vs HLA-1 AG mismatched related donor

Risk of relapse during the unrelated donor coordination period biases comparisons between allogeneic hematopoietic stem cell transplantation from an HLA 8 of 8 allele-matched unrelated donor (8/8 MUD) and that...

J Kanda, S Fuji, S Kato, A Takami, J Tanaka, K Miyamura, K Ohashi… in Blood Cancer Journal (2014)

Article

Segregation of a QTL cluster for home-cage activity using a new map** method based on regression analysis of congenic mouse strains

Recent genetic studies have shown that genetic loci with significant effects in whole-genome quantitative trait loci (QTL) analyses were lost or weakened in congenic strains. Characterisation of the genetic ba...

S Kato, A Ishii, A Nishi, S Kuriki, T Koide in Heredity (2014)

Article

Effects of KIR ligand incompatibility on clinical outcomes of umbilical cord blood transplantation without ATG for acute leukemia in complete remission

To clarify the effect of killer cell immunoglobulin-like receptor (KIR) ligand incompatibility on outcomes of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) patients in complete remission ...

J Tanaka, Y Morishima, Y Takahashi, T Yabe, K Oba, S Takahashi… in Blood Cancer Journal (2013)

Article

Multifunctional transcription factor TFII-I is an activator of BRCA1 function

The TFII-I is a multifunctional transcriptional factor known to bind specifically to several DNA sequence elements and to mediate growth factor signalling. A microdeletion at the chromosomal location 7q11.23 e...

M Tanikawa, O Wada-Hiraike, S Nakagawa, A Shirane, H Hiraike… in British Journal of Cancer (2011)

Article

Identification of DBC1 as a transcriptional repressor for BRCA1

DBC1/KIAA1967 (deleted in breast cancer 1) is a putative tumour-suppressor gene cloned from a heterozygously deleted region in breast cancer specimens. Caspase-dependent processing of DBC1 promotes apoptosis, and...

H Hiraike, O Wada-Hiraike, S Nakagawa, S Koyama, Y Miyamoto… in British Journal of Cancer (2010)

Article

Phase I/II study of sequential therapy with irinotecan and S-1 for metastatic colorectal cancer

Both irinotecan (CPT-11) and S-1 are active against colorectal cancer; however, as S-1 is a prodrug of 5-fluorouracil (5-FU), 5-FU and its metabolites might inhibit the antitumour effect of CPT-11. Therefore, ...

T Yoshioka, S Kato, M Gamoh, N Chiba, T Suzuki, N Sakayori… in British Journal of Cancer (2009)

Article

Independent prognostic value of somatic TP53gene mutations in 1794 breast cancer patients

M Olivier, A Langerød, P Carrieri, J Bergh, S Klaar, J Eyfjord… in Breast Cancer Research (2005)

Article

The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor α

The DNA mismatch repair gene is a key regulator in the elimination of base–base mismatches and insertion/deletion loops (IDLs). Human MutS homologue 2 (hMSH2), originally identified as a human homologue of the...

O Wada-Hiraike, T Yano, T Nei, Y Matsumoto, K Nagasaka… in British Journal of Cancer (2005)

Article

Allelic diversity of S-RNase at the self-incompatibility locus in natural flowering cherry populations (Prunus lannesiana var. speciosa)

In the Rosaceae family, which includes Prunus, gametophytic self-incompatibility (GSI) is controlled by a single multiallelic locus (S-locus), and the S-locus product expressed in the pistils is a glycoprotein wi...

S Kato, Y Mukai in Heredity (2004)

Article

Diagnosis of Japanese patients with HHH syndrome by molecular genetic analysis: a common mutation, R179X

Patients with mitochondrial ornithine transporter deficiency (or HHH syndrome) present with various neurological symptoms, including mental retardation, spastic paraparesis with pyramidal signs, cerebellar at...

T. Miyamoto, N. Kanazawa, S. Kato, M. Kawakami, Y. Inoue… in Journal of Human Genetics (2001)

Article

Haemagglutinin-esterase protein (HE) of murine corona virus: DVIMD (diarrhea virus of infant mice)

The acetylesterase (AE) activity of DVIM (diarrhea virus of infant mice) was assigned to the haemagglutinin-esterase (HE) protein. The substrate specificity was examined using the natural substrate bovine subm...

K. Sugiyama, M. Kasai, S. Kato, H. Kasai, K. Hatakeyama in Archives of Virology (1998)