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Article
Prevention of Chemotherapy-Induced Nausea and Emesis in Patients Responding Poorly to Previous Antiemetic Therapy
In a multicentre trial, 78 patients with a variety of malignancies, who had experienced insufficient control of emesis (⩾ 3 episodes within 24 hours) while receiving standard antiemetics during previous chemot...
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Article
Cellular signaling by cyclosporine A in contractile cells: interactions with atrial natriuretic peptide
Immunosuppressive therapy with cyclosporine A (CyA) may be associated with severe side effects such as nephrotoxicity and arterial hypertension. The partial reversibility of these effects suggests that they ar...
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Chapter and Conference Paper
Farbskalen zur Messung von Befindlichkeit und Lebensqualität
Um die subjektive Wirkung einer Maßnahme zu beurteilen (besonders im Bereich klinischer Fragestellungen), ist der Fragebogen nach wie vor die wichtigste Methode. Wie weit die Einführung von Farben bzw. Farbkrä...
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Article
Comparison of three tropisetron-containing antiemetic regimens in the prophylaxis of acute and delayed chemotherapy-induced emesis and nausea
There is still controversy as to what constitutes the optimal therapy for acute and delayed chemotherapy-induced emesis and nausea. We conducted a three-armed randomized multi-centre study in 193 chemotherapy...
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Article
Berücksichtigung von ferromagnetischem Material in der FNM durch Einführung von Magnetisierungsstromdichten
Die Beschreibung von ferromagnetischem Material durch Permeabilitäten ist äquivalent zum Modell mit Magnetisierungsströmen und Oberflächenstromdichten. Diese Äquivalenz wird in der Finiten Netzwerke Methode (F...
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Article
Multiparametric microsensor chips for screening applications
The identification of drug targets for pharmaceutical screening can be greatly accelerated by gene databases and expression studies. The identification of lead-ing compounds from growing libraries is realized...
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Article
Open AccessHomogeneity versus diversity: inhibition of plasma PAI-1 in murine sepsis proved lethal in homogeneous cohorts but not in all-inclusive populations
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Article
Open AccessSplenectomy modulates early immuno-inflammatory responses to trauma-hemorrhage and protects mice against secondary sepsis
In polytrauma patients, the impact of splenectomy is equivocal, ranging from negative to protective. We investigated the impact of splenectomy on immune responses in the 1st-hit polytrauma alone and on survival i...