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  1. Article

    Open Access

    Splenectomy modulates early immuno-inflammatory responses to trauma-hemorrhage and protects mice against secondary sepsis

    In polytrauma patients, the impact of splenectomy is equivocal, ranging from negative to protective. We investigated the impact of splenectomy on immune responses in the 1st-hit polytrauma alone and on survival i...

    S. Drechsler, J. Zipperle, P. Rademann, M. Jafarmadar, A. Klotz… in Scientific Reports (2018)

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  2. Article

    Open Access

    Homogeneity versus diversity: inhibition of plasma PAI-1 in murine sepsis proved lethal in homogeneous cohorts but not in all-inclusive populations

    P Raeven, KM Weixelbaumer, S Drechsler, A Klotz, M Jafarmadar, A Khadem… in Critical Care (2012)

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  3. No Access

    Article

    Multiparametric microsensor chips for screening applications

    The identification of drug targets for pharmaceutical screening can be greatly accelerated by gene databases and expression studies. The identification of lead-ing compounds from growing libraries is realized...

    R. Ehret, W. Baumann, M. Brischwein… in Fresenius' Journal of Analytical Chemistry (2001)

  4. No Access

    Article

    Berücksichtigung von ferromagnetischem Material in der FNM durch Einführung von Magnetisierungsstromdichten

    Die Beschreibung von ferromagnetischem Material durch Permeabilitäten ist äquivalent zum Modell mit Magnetisierungsströmen und Oberflächenstromdichten. Diese Äquivalenz wird in der Finiten Netzwerke Methode (F...

    A. Farschtschi, J. Plontke, H. -J. Roscher, S. Drechsler in Electrical Engineering (1998)

  5. No Access

    Article

    Comparison of three tropisetron-containing antiemetic regimens in the prophylaxis of acute and delayed chemotherapy-induced emesis and nausea

     There is still controversy as to what constitutes the optimal therapy for acute and delayed chemotherapy-induced emesis and nausea. We conducted a three-armed randomized multi-centre study in 193 chemotherapy...

    S. Drechsler, U. Bruntsch, J. Eggert, J. Grote-Kiehn, H. Gosse… in Supportive Care in Cancer (1997)

  6. No Access

    Chapter and Conference Paper

    Farbskalen zur Messung von Befindlichkeit und Lebensqualität

    Um die subjektive Wirkung einer Maßnahme zu beurteilen (besonders im Bereich klinischer Fragestellungen), ist der Fragebogen nach wie vor die wichtigste Methode. Wie weit die Einführung von Farben bzw. Farbkrä...

    D. Welzel, Prof. Dr. R. Kohnen, H.-P. Krüger… in Befunderhebung in der Psychiatrie: Lebensq… (1996)

  7. No Access

    Article

    Cellular signaling by cyclosporine A in contractile cells: interactions with atrial natriuretic peptide

    Immunosuppressive therapy with cyclosporine A (CyA) may be associated with severe side effects such as nephrotoxicity and arterial hypertension. The partial reversibility of these effects suggests that they ar...

    Dr. H. H. Meyer-Lehnert, D. Bokemeyer, U. Friedrichs… in The clinical investigator (1993)

  8. No Access

    Article

    Prevention of Chemotherapy-Induced Nausea and Emesis in Patients Responding Poorly to Previous Antiemetic Therapy

    In a multicentre trial, 78 patients with a variety of malignancies, who had experienced insufficient control of emesis (⩾ 3 episodes within 24 hours) while receiving standard antiemetics during previous chemot...

    Dr U. Bruntsch, S. Drechsler, E. Hiller, W. Eiermann, A. H. Tulusan, M. Bühner… in Drugs (1992)