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Open AccessIdentification of early and intermediate biomarkers for ARDS mortality by multi-omic approaches
The lack of successful clinical trials in acute respiratory distress syndrome (ARDS) has highlighted the unmet need for biomarkers predicting ARDS mortality and for novel therapeutics to reduce ARDS mortality....
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Article
CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression
Overexpression of Cys2His2 zinc-finger 322A (ZNF322A) oncogenic transcription factor is associated with lung tumorigenesis. However, the mechanism of ZNF322A overexpression remains poorly understood. Here, we ...
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Article
Open AccessErratum: Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer
Correction to: Oncogene (2016) 35, 2357–2369; doi: 10.1038/onc.2015.296 Following the publication of this paper, the authors noted some errors in Figure 8e. The misplaced images arose from errors in rearrangin...
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Article
Open AccessErratum: Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer
Correction to: Oncogene (2016) 35, 2357–2369; doi:10.1038/onc.2015.296; published online 17 August 2015 Since the publication of the above article, the authors would like to correct the order of the authors in...
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Article
New Ni(II) and Co(II) coordination compounds construction from the ditopic 1,2,3-triazol-based aromatic heterocyclic polycarboxylic ligand
Mononuclear compound I ([Co(Ptia)2(H2O)4] • H2O) and 1D chain compound II ([Ni4(Cptia)4(H2O)12]∞) have been constructed from the new ditopic 1,2,3-trazol-based aromatic heterocyclic carboxylic ligand, 4-(4-carbox...
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Article
Open AccessOncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer
ZNF322A encoding a classical Cys2His2 zinc finger transcription factor was previously revealed as a potential oncogene in lung cancer patients. However, the oncogenic role of ZNF322A and its underlying mechanism ...
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Article
Transcriptome analysis of human breast cancer cell lines MCF-7 and MDA-MB-435 by RNA-Seq
The transcriptomic profiles of human breast cancer cell lines MCF-7 and MDA-MB-435 were investigated using the next-generation RNA sequencing (RNA-Seq). The DESeq package was used to screen the differentially ...
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Article
Open AccessEndocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: a Gynaecological Oncology Group Study
Lobular endocervical glandular hyperplasia (LEGH) is a rare lesion of the uterine cervix. It has been proposed that LEGH may represent a precursor lesion to a group of mucinous adenocarcinoma with gastric phen...
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Article
Spectral editing of two-dimensional magic-angle-spinning solid-state NMR spectra for protein resonance assignment and structure determination
Several techniques for spectral editing of 2D 13C–13C correlation NMR of proteins are introduced. They greatly reduce the spectral overlap for five common amino acid types, thus simplifying spectral assignment an...
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Article
Open AccessCarbonic anhydrase IX (CA-IX) and high-risk human papillomavirus (H-HPV) as diagnostic biomarkers of cervical dysplasia/neoplasia in Japanese women with a cytologic diagnosis of atypical glandular cells (AGC): a Gynecologic Oncology Group (GOG) Study
High-risk human papillomavirus (H-HPV) infection is linked to cervical neoplasia but its role in detecting cervical glandular lesions (GLs) is unclear. Carbonic anhydrase IX (CA-IX) is a hypoxic biomarker that...
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Article
Magnetoresistance of epitaxial cobalt films
The magnetoresistance of epitaxial fcc Co(110) on MgO(110) is found to depend strongly on crystallographic orientation; at 10K its relative magnitude is ten times larger than for Co(100) on MgO(100). The thick...