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  1. No Access

    Article

    PAX3-NCOA2 fusion gene has a dual role in promoting the proliferation and inhibiting the myogenic differentiation of rhabdomyosarcoma cells

    We analyzed a complex chromosomal translocation in a case of embryonal rhabdomyosarcoma (RMS) and showed that it generates the fusion gene PAX3 (paired box 3)-NCOA2 (nuclear receptor coactivator 2). To understand...

    H Yoshida, M Miyachi, K Sakamoto, K Ouchi, S Yagyu, K Kikuchi, Y Kuwahara… in Oncogene (2014)

  2. No Access

    Article

    Bortezomib sensitizes non-small cell lung cancer to mesenchymal stromal cell-delivered inducible caspase-9-mediated cytotoxicity

    Delivery of suicide genes to solid tumors represents a promising tumor therapy strategy. However, slow or limited killing by suicide genes and ineffective targeting of the tumor has reduced effectiveness. We h...

    M Ando, V Hoyos, S Yagyu, W Tao, C A Ramos, G Dotti, M K Brenner… in Cancer Gene Therapy (2014)

  3. Article

    Open Access

    RASSF1A hypermethylation in pretreatment serum DNA of neuroblastoma patients: a prognostic marker

    The tumour suppressor gene RASSF1A is known to be frequently silenced by promoter hypermethylation in neuroblastoma tumours. Here we explored the possible prognostic significance of aberrant promoter hypermethyla...

    A Misawa, S Tanaka, S Yagyu, K Tsuchiya, T Iehara, T Sugimoto… in British Journal of Cancer (2009)

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