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Article
Recent trace element contamination in a rural crater lake, NW Mexico
Lakes provide a wide range of ecosystem services that are increasingly at risk because of multiple anthropogenic pressures. Santa María del Oro crater lake lies in rural northwest Mexico and is of interest for...
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Article
Historical reconstruction of sediment accumulation rates as an indicator of global change impacts in a tropical crater lake
Lakes are effective sentinels of global change owing to their sensitivity to land-use changes and climate variability in their catchment. Santa María del Oro Lake (SAMO, NW Mexico) is of interest both for glob...
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Article
Open AccessCorrection: Management of relapsed and refractory multiple myeloma: novel agents, antibodies, immunotherapies and beyond
Following the publication of this article the authors noted that the MRD data under the Table 1 column “Remark” of Aspire should go to that of Pollux. The authors wish to apologize for any inconvenience caused...
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Article
Open AccessManagement of relapsed and refractory multiple myeloma: novel agents, antibodies, immunotherapies and beyond
Despite enormous advances, management of multiple myeloma (MM) remains challenging. Multiple factors impact the decision to treat or which regimen to use at MM relapse/progression. Recent major randomized cont...
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Article
Third International workshop on the biology, prevention, and treatment of relapse after stem cell transplantation
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Article
Open AccessPotential ash impact from Antarctic volcanoes: Insights from Deception Island’s most recent eruption
Ash emitted during explosive volcanic eruptions may disperse over vast areas of the globe posing a threat to human health and infrastructures and causing significant disruption to air traffic. In Antarctica, a...
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Article
Allogeneic hematopoietic cell transplantation in patients with AML not achieving remission: potentially curative therapy
Patients with acute myeloid leukemia (AML) who fail to achieve complete remission (CR) have a dismal prognosis. Although data suggest that durable remissions can be achieved in approximately 30% of patients wi...
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Article
Open AccessLong-term event-free and overall survival after risk-adapted melphalan and SCT for systemic light chain amyloidosis
Stem cell transplantation (SCT), an effective therapy for amyloid light chain (AL) amyloidosis patients, is associated with low treatment-related mortality (TRM) with appropriate patient selection and risk-ada...
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Article
A sco** review of caregiver burden during allogeneic HSCT: lessons learned and future directions
The extant literature documents burden among caregivers of patients undergoing a hematopoietic stem cell transplantation (HSCT), but little is known about the burden of caregivers of patients receiving outpati...
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Article
Peer review in hematopoietic cell transplantation: are we doing our fair share?
Peer review is believed to be important in maintaining the quality and integrity of research in academic endeavors. Recently, the value of the current peer review process, which is more than 100 years old has ...
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Article
MRD-driven treatment paradigm for newly diagnosed transplant eligible multiple myeloma patients
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Article
A novel reduced intensity conditioning regimen for patients with high-risk hematological malignancies undergoing allogeneic stem cell transplantation
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Article
Upfront plerixafor plus G-CSF versus cyclophosphamide plus G-CSF for stem cell mobilization in multiple myeloma: efficacy and cost analysis study
Cyclophosphamide plus G-CSF (C+G-CSF) is one of the most widely used stem cell (SC) mobilization regimens for patients with multiple myeloma (MM). Plerixafor plus G-CSF (P+G-CSF) has demonstrated superior SC m...
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Article
The effects of the NAO on the ice phenology of Spanish alpine lakes
Three Spanish alpine lakes located in the Central Range (Peñalara Lake and Cimera Lake) and the Pyrenees (Redon Lake) are selected to understand the effects of the North Atlantic Oscillation (NAO) on ice pheno...
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Article
Allo-SCT for myelofibrosis: reversing the chronic phase in the JAK inhibitor era?
At present, allo-SCT is the only curative treatment for patients with myelofibrosis (MF). Unfortunately, a significant proportion of candidate patients are considered transplant ineligible due to their poor ge...
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Article
Comparison of outcomes at two institutions of patients with ALL receiving ex vivo T-cell-depleted or unmodified allografts
We compared outcomes of adult patients receiving T-cell-depleted (TCD) hematopoietic SCT (HCT) without additional GVHD prophylaxis at Memorial Sloan Kettering Cancer Center (MSKCC, N=52), with those of patients r...
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Article
Safety of voriconazole and sirolimus coadministration after allogeneic hematopoietic SCT
Antifungal prophylaxis with azoles is considered standard in allogeneic hematopoietic SCT (allo-HSCT). Although sirolimus is being used increasingly for the prevention of GVHD, it is a substrate of CYP3A4, whi...
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Article
Donor–recipient allele-level HLA matching of unrelated cord blood units reveals high degrees of mismatch and alters graft selection
The feasibility of selecting cord blood (CB) units at high-resolution HLA match has not been investigated. We analyzed the high-resolution donor–recipient HLA match of 100 double-unit 4–6/6 HLA-A,-B antigen, -...
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Article
Polyclonal immune activation and marrow plasmacytosis in multiple myeloma patients receiving long-term lenalidomide therapy: incidence and prognostic significance
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Article
Factors impacting stem cell mobilization failure rate and efficiency in multiple myeloma in the era of novel therapies: experience at Memorial Sloan Kettering Cancer Center
Thalidomide, lenalidomide and bortezomib have increasingly been incorporated in first-line induction therapies for multiple myeloma. Concerns regarding the impact of these agents, especially lenalidomide, on s...