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Article
Peer review in hematopoietic cell transplantation: are we doing our fair share?
Peer review is believed to be important in maintaining the quality and integrity of research in academic endeavors. Recently, the value of the current peer review process, which is more than 100 years old has ...
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Chapter
Design of peptidic and non-peptidic CD4 inhibitors as novel immunotherapeutic agents [1–5]
We have proposed the CC’ loop as an important functional epitope on the CD4 surface for intermolecular binding, and found that small peptide mimics of this epitope are sufficient to interrupt a larger protein-...
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Article
Structure based design and characterization of peptides that inhibit IgE binding to its high-affinity receptor
We have designed synthetic peptide inhibitors of the interaction between IgE and its high affinity receptor, FcεRI. The structure of the second domain of CD2 was used as a modelling template for the second α-c...
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Chapter
H-2-Restriction of T Cells Mediating Lethal Graft-Versus-Host-Disease to Minor Histocompatibility Determinants
Although the etiology and pathogenesis of graft-versus-host disease (GVHD) continues to excite controversy and speculation, it is now generally accepted that the disease reflects alloaggres-sion mediated by ma...
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Article
T cell recognition of antigen in vivo: Role of the H-2 complex