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    Article

    Knowledge, attitudes, and perceived barriers towards genetic testing across three rural Illinois communities

    Genetic testing is becoming more prevalent in detecting risk and guiding cancer treatment in our increasingly personalized medicine model. However, few studies have examined underserved populations’ perception...

    A. J. Fogleman, W. E. Zahnd, A. E. Lipka, R. S. Malhi in Journal of Community Genetics (2019)

  2. Article

    Open Access

    Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome

    The CXCL10/CXCR3 signalling mediates paracrine interactions between tumour and stromal cells that govern leukocyte trafficking and angiogenesis. Emerging data implicate noncanonical CXCL10/CXCR3 signalling in ...

    S C Wightman, A Uppal, S P Pitroda, S Ganai, B Burnette in British Journal of Cancer (2015)

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    Article

    In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis

    Motile bacteria can overcome diffusion resistances that substantially reduce the efficacy of standard cancer therapies. Many reports have also recently described the ability of Salmonella to deliver therapeutic m...

    S Ganai, R B Arenas, J P Sauer, B Bentley, N S Forbes in Cancer Gene Therapy (2011)

  4. Article

    Open Access

    Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice

    An effective cancer therapeutic must selectively target tumours with minimal systemic toxicity. Expression of a cytotoxic protein using Salmonella typhimurium would enable spatial and temporal control of delivery...

    S Ganai, R B Arenas, N S Forbes in British Journal of Cancer (2009)