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Article
Validation of an endoscopic anastomotic grading score as an intraoperative method for assessing stapled rectal anastomoses
Anastomotic leak is a dreaded complication of colorectal surgery. An endoscopic grading score of the perianastomotic mucosa has been previously developed at our institution (UCI) to assess colorectal anastomot...
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Article
Synthesis and Computational Studies of Molecular Structure and Vibrational Spectra of 2-Amino-4-(4-Nitrophenyl)-4H-Pyrano-[3,2-H]Quinolines
We have disclosed the synthesis of pyranoquinoline derivatives via a one-pot reaction of 4-nitro benz aldehyde, malononitrile/ethyl cyanoacetate and 8-hydroxyquinoline using 30 mol.% DMAP in ethanol under refl...
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Article
Open AccessOncogenic CXCL10 signalling drives metastasis development and poor clinical outcome
The CXCL10/CXCR3 signalling mediates paracrine interactions between tumour and stromal cells that govern leukocyte trafficking and angiogenesis. Emerging data implicate noncanonical CXCL10/CXCR3 signalling in ...
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Article
Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor
NF-κB proteins play a central and subunit-specific role in the response to DNA damage. Previous work identified p50/NF-κB1 as being necessary for cytotoxicity in response to DNA alkylation damage. Given the im...
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Article
Evaluation of Photodynamic Efficacy of Chlorin p 6 Bound to Amine-Modified Silica Nanoparticles in Colon and Oral Cancer Cell Lines
We report results of our studies on cellular uptake and phototoxicity of free chlorin p 6 (Cp 6) and Cp 6 bound to amine-modified silica nanoparticles (Cp ...
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Article
Manipulation of microparticles and red blood cells using optoelectronic tweezers
We report the development of an optoelectronic tweezers set-up which works by light-induced dielectrophoresis mechanism to manipulate microparticles. We used thermal evaporation technique for coating the organ...