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  1. Article

    Open Access

    High-throughput sequencing of nodal marginal zone lymphomas identifies recurrent BRAF mutations

    Nodal marginal zone lymphoma (NMZL) is a rare small B-cell lymphoma lacking disease-defining phenotype and precise diagnostic markers. To better understand the mutational landscape of NMZL, particularly in com...

    V. Pillonel, D. Juskevicius, C. K. Y. Ng, A. Bodmer, A. Zettl, D. Jucker in Leukemia (2018)

  2. No Access

    Article

    Quality assurance trials for Ki67 assessment in pathology

    Ki67 is a broadly used proliferation marker in surgical pathology with an obvious need for standardization to improve reproducibility of assessment. Here, we present results of the so far only existing round r...

    M. Raap, S. Ließem, J. Rüschoff, A. Fisseler-Eckhoff, A. Reiner in Virchows Archiv (2017)

  3. No Access

    Article

    Distinct genetic evolution patterns of relapsing diffuse large B-cell lymphoma revealed by genome-wide copy number aberration and targeted sequencing analysis

    Recurrences of diffuse large B-cell lymphomas (DLBCL) result in significant morbidity and mortality, but their underlying genetic and biological mechanisms are unclear. Clonal relationship in DLBCL relapses so...

    D Juskevicius, T Lorber, J Gsponer, V Perrina, C Ruiz, F Stenner-Liewen in Leukemia (2016)

  4. No Access

    Article

    Follicular lymphoma transformation into histiocytic sarcoma: indications for a common neoplastic progenitor

    P Brunner, A Rufle, S Dirnhofer, A Lohri, N Willi, G Cathomas, A Tzankov in Leukemia (2014)

  5. Article

    Open Access

    A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma

    Dysregulated expression of factors that control protein synthesis is associated with poor prognosis of many cancers, but the underlying mechanisms are not well defined. Analysis of the diffuse large B-cell lym...

    E Horvilleur, T Sbarrato, K Hill, R V Spriggs, M Screen, P J Goodrem, K Sawicka in Leukemia (2014)

  6. Article

    Open Access

    P60. Microtubule-depolymerising agents used in antibody-drug-conjugates induce anti-tumour immunity by stimulation of dendritic cells

    K Martin, P Mueller, S Theurich, S Savic in Journal for ImmunoTherapy of Cancer (2014)

  7. No Access

    Article

    MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma

    Myeloid cell leukemia-1 (MCL1) is an anti-apoptotic member of the BCL2 family that is deregulated in various solid and hematological malignancies. However, its role in the molecular pathogenesis of diffuse lar...

    S-S Wenzel, M Grau, C Mavis, S Hailfinger, A Wolf, H Madle, G Deeb, B Dörken in Leukemia (2013)

  8. No Access

    Article

    GVHD after allogeneic haematopoietic SCT for AML: angiogenesis, vascular endothelial growth factor and VEGF receptor expression in the BM

    There is increasing evidence suggesting that both angiogenesis and endothelial injury are involved in GVHD. To study the dynamics of angiogenesis, we examined 26 patients with AML who had undergone allogeneic ...

    M Medinger, A Tichelli, C Bucher, J Halter, S Dirnhofer in Bone Marrow Transplantation (2013)

  9. Article

    Leukemia cutis preceding systemic relapse of acute myeloid leukemia

    M. Stern, J. Halter, A. Buser, A. Rovò, S. Dirnhofer in International Journal of Hematology (2008)

  10. No Access

    Article

    Legionella bozemanii, an Elusive Agent of Fatal Cavitary Pneumonia

    A 67-year-old patient died of Legionella bozemanii pneumonia with negative urinary antigen and negative serology. Cystic lesions in pneumonia of unknown origin should lead to the differential diagnosis of L. boze...

    A. Widmer, P. Hohl, S. Dirnhofer, S. Bassetti, S. Marsch, R. Frei in Infection (2007)

  11. No Access

    Article

    Paracrine promotion of tumor development by the TNF ligand APRIL in Hodgkin's Disease

    J Schwaller, P Went, T Matthes, S Dirnhofer, O Donze, P Mhawech-Fauceglia in Leukemia (2007)

  12. Article

    Open Access

    Immunohistochemical detection of micrometastasis and disseminated tumor cells in microscopically tumor free lymph nodes

    H Adams, S Dirnhofer in Diagnostic Pathology (2007)

  13. No Access

    Article

    Rare KIT (CD117) expression in multiple myeloma abrogates the usefulness of imatinib mesylate treatment

    Imatinib mesylate blocks the tyrosine kinase activity of KIT (CD117) and is an effective treatment for gastrointestinal stromal tumors. In multiple myeloma, KIT expression has been detected by flow cytometry i...

    A. Lugli, P. Went, B. Khanlari, Z. Nikolova, S. Dirnhofer in Virchows Archiv (2004)

  14. No Access

    Chapter

    Probing Human Follicle Stimulating Hormone with Monoclonal Antibodies and Synthetic Peptides

    The antigenic topography of the closely related molecules human follicle stimulating hormone (hFSH), human chorionic gonadotropin (hCG), and human luteinizing hormone (hLH) was previously elucidated (1–3) with...

    P. Berger, S. Dirnhofer, R. Klieber, R. Frank, G. Wick in Follicle Stimulating Hormone (1992)