20 Result(s)

Article

Routinemäßige zielgerichtete Hochdurchsatzsequenzierung von lymphoproliferativen Erkrankungen

Im Gegensatz zu anderen Tumorentitäten wie dem Lungenkarzinom, dem Melanom oder gynäkologischen und gastrointestinalen Tumoren ist der routinemäßige Einsatz von Mutationsanalysen mittels Hochdurchsatzsequenzie...

PD. Dr. T. Menter, S. Dirnhofer, A. Tzankov in Der Pathologe (2020)

Article

Quality assurance trials for Ki67 assessment in pathology

Ki67 is a broadly used proliferation marker in surgical pathology with an obvious need for standardization to improve reproducibility of assessment. Here, we present results of the so far only existing round r...

M. Raap, S. Ließem, J. Rüschoff, A. Fisseler-Eckhoff, A. Reiner… in Virchows Archiv (2017)

Article

Abdominale Beschwerden und Hypertonus bei einem 55‑jährigen Patienten

Ein 55-jähriger Patient unter Testosterondauertherapie bei Hypogonadismus stellte sich mit abdominalen Beschwerden und erhöhten Blutdruckwerten vor. Klinisch imponierte eine Plethora, im Labor sahen wir eine P...

Dr. T. Kofler, F. Yueksel, S. Dirnhofer, M. Y. Donath, M. Trendelenburg in Der Internist (2017)

Article

Distinct genetic evolution patterns of relapsing diffuse large B-cell lymphoma revealed by genome-wide copy number aberration and targeted sequencing analysis

Recurrences of diffuse large B-cell lymphomas (DLBCL) result in significant morbidity and mortality, but their underlying genetic and biological mechanisms are unclear. Clonal relationship in DLBCL relapses so...

D Juskevicius, T Lorber, J Gsponer, V Perrina, C Ruiz, F Stenner-Liewen… in Leukemia (2016)

Article

Follicular lymphoma transformation into histiocytic sarcoma: indications for a common neoplastic progenitor

P Brunner, A Rufle, S Dirnhofer, A Lohri, N Willi, G Cathomas, A Tzankov… in Leukemia (2014)

Article

MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma

Myeloid cell leukemia-1 (MCL1) is an anti-apoptotic member of the BCL2 family that is deregulated in various solid and hematological malignancies. However, its role in the molecular pathogenesis of diffuse lar...

S-S Wenzel, M Grau, C Mavis, S Hailfinger, A Wolf, H Madle, G Deeb, B Dörken… in Leukemia (2013)

Article

GVHD after allogeneic haematopoietic SCT for AML: angiogenesis, vascular endothelial growth factor and VEGF receptor expression in the BM

There is increasing evidence suggesting that both angiogenesis and endothelial injury are involved in GVHD. To study the dynamics of angiogenesis, we examined 26 patients with AML who had undergone allogeneic ...

M Medinger, A Tichelli, C Bucher, J Halter, S Dirnhofer… in Bone Marrow Transplantation (2013)

Article

Normales Knochenmark und häufige reaktive Veränderungen

Die histologische Knochenmarkuntersuchung spielt, wegen ihrer großen Aussagekraft bei relativ geringem Aufwand eine bedeutende Rolle in der Diagnostik von hämatologischen und nichthämatologischen Erkrankungen....

Prof. Dr. A. Tzankov, S. Dirnhofer, C. Beham-Schmid in Der Pathologe (2012)

Article

Legionella bozemanii, an Elusive Agent of Fatal Cavitary Pneumonia

A 67-year-old patient died of Legionella bozemanii pneumonia with negative urinary antigen and negative serology. Cystic lesions in pneumonia of unknown origin should lead to the differential diagnosis of L. boze...

A. Widmer, P. Hohl, S. Dirnhofer, S. Bassetti, S. Marsch, R. Frei in Infection (2007)

Article

Paracrine promotion of tumor development by the TNF ligand APRIL in Hodgkin's Disease

J Schwaller, P Went, T Matthes, S Dirnhofer, O Donze, P Mhawech-Fauceglia… in Leukemia (2007)

Article

Rare KIT (CD117) expression in multiple myeloma abrogates the usefulness of imatinib mesylate treatment

Imatinib mesylate blocks the tyrosine kinase activity of KIT (CD117) and is an effective treatment for gastrointestinal stromal tumors. In multiple myeloma, KIT expression has been detected by flow cytometry i...

A. Lugli, P. Went, B. Khanlari, Z. Nikolova, S. Dirnhofer in Virchows Archiv (2004)

Article

Papillär differenzierte Nierentumoren

Das metanephrogene Adenom ist ein seltener gutartiger Nierentumor. Die Differenzialdiagnose gegenüber tubulopapillären Adenomen und papillären Nierenzellkarzinomen ist teilweise schwierig. In der vorliegenden ...

A. Lugli, F. Stoffel, L. Terracciano, S. Dirnhofer, M. Mihatsch, H. Moch in Der Pathologe (2002)

Article

Urotheliale Tumoren und Präneoplasien Diagnostische Probleme und deren klinische Konsequenzen

H. Rogatsch, S. Dirnhofer, H. Feichtinger in Der Pathologe (1998)

Chapter

Probing Human Follicle Stimulating Hormone with Monoclonal Antibodies and Synthetic Peptides

The antigenic topography of the closely related molecules human follicle stimulating hormone (hFSH), human chorionic gonadotropin (hCG), and human luteinizing hormone (hLH) was previously elucidated (1–3) with...

P. Berger, S. Dirnhofer, R. Klieber, R. Frank, G. Wick in Follicle Stimulating Hormone (1992)