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  1. No Access

    Article

    Haplotype-aware analysis of somatic copy number variations from single-cell transcriptomes

    Genome instability and aberrant alterations of transcriptional programs both play important roles in cancer. Single-cell RNA sequencing (scRNA-seq) has the potential to investigate both genetic and nongenetic ...

    Teng Gao, Ruslan Soldatov, Hirak Sarkar, Adam Kurkiewicz… in Nature Biotechnology (2023)

  2. No Access

    Article

    RNA velocity of single cells

    RNA abundance is a powerful indicator of the state of individual cells. Single-cell RNA sequencing can reveal RNA abundance with high quantitative accuracy, sensitivity and throughput1. However, this approach cap...

    Gioele La Manno, Ruslan Soldatov, Amit Zeisel, Emelie Braun, Hannah Hochgerner… in Nature (2018)