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Open AccessGenetic analysis of oligo-recurrence breast cancer: correlation with clinical outcomes
We aimed to identify the relationship between the genomic characteristics and clinical outcomes of oligo-metastatic breast cancer.
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Open AccessNail pigmentation induced by chemotherapy: an observational study of patients with early-stage breast cancer
Chemotherapy-induced nail pigmentation is a common adverse effect, but prospective studies focussing on its onset, recovery, and severity are few. We aim to evaluate the pattern of chemotherapy-induced nail pi...
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Article
Open AccessRetro-enantio isomer of angiopep-2 assists nanoprobes across the blood-brain barrier for targeted magnetic resonance/fluorescence imaging of glioblastoma
Glioblastoma (GBM), one of the most common primary intracranial malignant tumours, is very difficult to be completely excised by surgery due to its irregular shape. Here, we use an MRI/NIR fluorescence dual-mo...
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Open AccessThe STING1 network regulates autophagy and cell death
Cell death and immune response are at the core of life. In past decades, the endoplasmic reticulum (ER) protein STING1 (also known as STING or TMEM173) was found to play a fundamental role in the production of...
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Open AccessCPSF4 promotes triple negative breast cancer metastasis by upregulating MDM4
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Open AccessComorbidity in lung cancer patients and its association with hospital readmission and fatality in China
Comorbidity has been established as one of the important predictors of poor prognosis in lung cancer. In this study, we analyzed the prevalence of main comorbidities and its association with hospital readmissi...
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Open AccessComorbidity in lung cancer patients and its association with medical service cost and treatment choice in China
It is evident that comorbidity exacerbate the complexity of the management of lung cancer, however, limited research has been conducted to investigate the impact of comorbidity on health service utilization an...
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Open AccessErratum to: 53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells
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Open Access53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells
Mutations in DNA damage response factors BRCA1 and BRCA2 confer sensitivity to poly(ADP-ribose) polymerase (PARP) inhibitors in breast and ovarian cancers. BRCA1/BRCA2-defective tumors can exhibit resistance t...