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Article
Open AccessPlasma-Free Blood as a Potential Alternative to Whole Blood for Transcriptomic Analysis
RNA sequencing (RNAseq) technology has become increasingly important in precision medicine and clinical diagnostics, and emerged as a powerful tool for identifying protein-coding genes, performing differential...
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Article
Open AccessExtend the benchmarking indel set by manual review using the individual cell line sequencing data from the Sequencing Quality Control 2 (SEQC2) project
Accurate indel calling plays an important role in precision medicine. A benchmarking indel set is essential for thoroughly evaluating the indel calling performance of bioinformatics pipelines. A reference samp...
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Article
Open AccessDevelopment and validation of nomogram for predicting early recurrence after radical gastrectomy of gastric cancer
After radical surgery, early detection of recurrence and metastasis is a crucial factor in enhancing the prognosis and survival of patients with gastric cancer (GC). Therefore, assessing the risk of recurrence...
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Article
Open AccessMulti-omics data integration using ratio-based quantitative profiling with Quartet reference materials
Characterization and integration of the genome, epigenome, transcriptome, proteome and metabolome of different datasets is difficult owing to a lack of ground truth. Here we develop and characterize suites of ...
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Article
Open AccessPrognostic significance of inflammatory and nutritional markers in perioperative period for patients with advanced gastric cancer
It has been reported that inflammatory and nutritional markers are related to prognosis in numerous malignancies. The present study analyzed the significance of these markers’ alterations during neoadjuvant ch...
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Chapter and Conference Paper
Research on a Centralized Thrust Deployment Method for Space Satellite Swarms
To improve the current deployment method for satellite swarms, this paper put forward a centralized thrust deployment method for space satellite swarms, which is low-cost, high-accuracy, easy to realize and fl...
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Chapter and Conference Paper
Fragmentation Technology of Spacecraft TT&C Resources Under Multi-constraint Condition
With the development of the world space industry, the number of spacecrafts in the future will increase much faster than the ground-based TT&C equipment and space-based TT&C capacity. In the case of SpaceX's S...
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Chapter and Conference Paper
Research on Satellite-to-Ground Integration Joint Mission Planning System for Mega-constellation Multi-user Remote Sensing Information Resource Guarantee
In order to meet the growing demands for earth remote sensing observation of the commercial space companies, promote the ability of rapid access to remote sensing product, further optimize resources using proc...
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Article
Open AccessPreoperative chemotherapy combined with para-aortic lymph node dissection has clinical value in the treatment of gastric cancer with para-aortic lymph node metastases
Lymph node metastases often occur in advanced gastric cancer, with some patients presenting with metastases in the para-aortic lymph nodes. There are persistent Controversies about the benefit of para-aortic l...
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Article
Open AccessAn intelligent recognition method of chromosome rearrangement patterns based on information entropy
Chromosome rearrangements play an important role in the speciation of plants and animals, and the recognition of chromosome rearrangement patterns is helpful to elucidate the mechanism of species differentiati...
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Article
Open AccessA comprehensive genomic and transcriptomic dataset of triple-negative breast cancers
Molecular subty** of triple-negative breast cancer (TNBC) is essential for understanding the mechanisms and discovering actionable targets of this highly heterogeneous type of breast cancer. We previously pe...
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Article
The energy density threshold evaluation for high-precision laser cleaning of the oxidized layer on 7075 aluminum alloy with 100 ns laser
The machining parameters are difficult to duplicate and apply among various equipment in 7075 aluminum laser cleaning. This is due to the non-uniform Gaussian beam being used as the laser source, and the previ...
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Article
Open AccessThe lncRNA DANCR promotes development of atherosclerosis by regulating the miR-214-5p/COX20 signaling pathway
Although long non-coding RNA differentiation antagonizing non-protein coding RNA (DANCR) has been reported to be involved in atherosclerosis (AS) development, its specific mechanism remains unclear.
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Article
Open AccessRational design of heterodimeric receptors capable of activating target signaling molecules
Intracellular signal transduction is regulated by a variety of transmembrane receptors. Many researchers have aimed to arbitrarily regulate the intracellular signaling and subsequent cell fate with artificial ...
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Article
Open AccessA recycling culture of Neochloris oleoabundans in a bicarbonate-based integrated carbon capture and algae production system with harvesting by auto-flocculation
A bicarbonate-based integrated carbon capture and algae production system (BICCAPS) uses carbonate to capture CO2 and produce bicarbonate for alkalihalophilic microalgal cultivation. In this process, carbonate is...
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Chapter and Conference Paper
Constructing a Decision-Support System for Safe Ship-Navigation Using a Bayesian Network
In a complicated sea environment, a ship needs experienced seafarers to steer it safely. Advancements in technology have not fundamentally reduced the number of accidents at sea. In deep-seated research and an...
