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Open AccessEffect of SGLT2 inhibition on salt-induced hypertension in female Dahl SS rats
Sodium-glucose co-transporters (SGLTs) in the kidneys play a pivotal role in glucose reabsorption. Several clinical and population-based studies revealed the beneficial effects of SGLT2 inhibition on hypertens...
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Article
Open AccessDHHC21 deficiency attenuates renal dysfunction during septic injury
Renal dysfunction is one of the most common complications of septic injury. One critical contributor to septic injury-induced renal dysfunction is renal vascular dysfunction. Protein palmitoylation serves as a...
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Article
Multiplexed derivatization strategy-based dummy molecularly imprinted polymers as sorbents for magnetic dispersive solid phase extraction of globotriaosylsphingosine prior to UHPLC-MS/MS quantitation
A new series of 9-plex chemical isotope-labeling reagents, levofloxacin-based mass tags (LMTs) named as LMT359, 360, 361, 362, 363, 373, 375, 376, and 378, was firstly designed and synthesized for the high-thr...
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Article
Fe3O4 nanoparticle-enabled mode-locking in an erbium-doped fiber laser
In this paper, we have proposed and demonstrated the generation of passively mode-locked pulses and dissipative soliton resonance in an erbium-doped fiber laser based on Fe3O4 nanoparticles as saturable absorbers...
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Impact of genetic and clinical factors on warfarin therapy in patients early after heart valve replacement surgery
Factors influencing responsiveness to warfarin at treatment onset time were not well identified in Chinese patients undergoing heart valve replacement. We sought to select the most relevant factors that associ...
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Book
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The Mature Media App in the Micro-communication Landscape—Development Report on China’s Microblog in 2014
Since 2014, the development of China’s microblog was affected by WeChat and other entirely a mobile network based new micro-communication platforms. Because Tencent began to shift its focus from WeChat to micr...
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Chapter
National Strategy: A New Stage in the Development of China’s New Media
China’s new media entered a new development stage in 2014. Online information security was elevated to become a matter of national strategic importance. Media convergence became an important part of if the cen...
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Article
Pressure induces intracellular calcium changes in juxtaglomerular cells in perfused afferent arterioles
Calcium (Ca2+) has an important role in nearly all types of cellular secretion, with a particularly novel role in the juxtaglomerular (JG) cells in the kidney. In JG cells, Ca2+ inhibits renin secretion, which is...
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Article
Cross-talk between arterioles and tubules in the kidney
In hypertension the pressure natriuresis set point is shifted to a higher pressure due to an increase in both renal vascular resistance and sodium (Na) reabsorption. The afferent arterioles (Af-Arts) and effer...
