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Open AccessRed blood cell distribution width is associated with sarcopenia risk in early-stage non-small cell lung cancer
Sarcopenia has received increasing attention in non-small cell lung cancer (NSCLC). Red blood cell distribution width (RDW) is a significant component of the complete blood count and indicates the heterogeneit...
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Article
Open AccessAssociation between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study
As a transmembrane protein, C-type lectin-like receptor 2 (CLEC-2) is mainly expressed on platelets and released into plasma after platelet activation. Activated platelets participate in the regulation of inna...
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Article
Open AccessPreoperative PDW levels predict pulmonary metastasis in patients with hepatocellular carcinoma
In hepatocellular carcinoma (HCC), pulmonary metastasis (PM) after hepatectomy is associated with poor clinical outcomes. The crucial phases of tumour cell proliferation, angiogenesis, and metastasis all entai...
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Article
Open AccessUtility of mean platelet volume in differentiating intrahepatic cholangiocarcinoma from hepatocellular carcinoma
Intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC) are the most prevalent histologic types of primary liver cancer. HCC and ICC differ in treatment and prognosis, warranting an effective ...
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Article
Open AccessAssociation between apoptosis inhibitor of macrophage and microsatellite instability status in colorectal cancer
The microsatellite instability (MSI) in colorectal cancer (CRC) has a more favorable clinical outcome and is characterized by highly upregulated expression of various immunological checkpoints than microsatell...
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Article
Open AccessReduced mean platelet volume levels predict shorter survival in patients with resectable pancreatic ductal adenocarcinoma and type 2 diabetes
Type 2 diabetes mellitus (T2DM) increased the risk of develo** pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) is the most common neoplastic disease originating from the pancreas. Increasing evide...
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Article
Preoperative mean platelet volume predicts survival in breast cancer patients with type 2 diabetes
Patients with type 2 diabetes mellitus (T2DM) have an increased risk of breast cancer (BC). Furthermore, growing evidence suggests that activated platelets play a crucial role in tumor and T2DM. Mean platelet ...
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Article
Open AccessMean platelet volume predicts survival in pancreatic cancer patients with synchronous liver metastases
Most pancreatic cancer (PC) patients manifest multiple liver metastases at the time of diagnosis. Activated platelets play a key role in tumor growth and tumor metastases. Mean platelet volume (MPV) is a plate...
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Article
Association of decreased mean platelet volume with renal cell carcinoma
Renal cell carcinoma (RCC) is the third most common genitourinary cancer. Activated platelets play a pivotal role in cancer development and progression. Altered mean platelet volume (MPV) has been reported in ...
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Article
Open AccessElevated mean platelet volume predicts poor prognosis in colorectal cancer
Altered mean platelet volume (MPV) is implicated in several malignancies. However, the clinicopathological significance and prognostic value of MPV in colorectal cancer (CRC) is still elusive. The purpose of t...
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Article
Open AccessLower mean platelet volume predicts poor prognosis in renal cell carcinoma
Altered mean platelet volume (MPV) is found in several malignancies. Remarkably, there is little consensus on using the value of MPV in the prognostic evaluations of renal cell carcinoma (RCC). The aim of this...
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Article
Open AccessPlatelet distribution width correlates with prognosis of non-small cell lung cancer
Platelets play a multifaceted role in cancer progression and metastasis. Mean platelet volume (MPV) and platelet distribution width (PDW) are commonly used platelet parameters from routine blood test. The aim ...
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Article
Open AccessIncreased platelet distribution width predicts poor prognosis in melanoma patients
Activated platelets promote cancer progression and metastasis. Nevertheless, the prognostic value of platelet indices in melanoma had been rarely reported. The aim of this study was to investigate the predicti...
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Article
Gallstone disease is associated with arterial stiffness progression
Gallstones have been linked to dyslipidemia, metabolic syndrome and cardiovascular disease. Arterial stiffness is an indicator of subclinical atherosclerosis. The aim of this study was to prospectively examine...
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Article
Association between whole blood viscosity and arterial stiffness in patients with type 2 diabetes mellitus
Type 2 diabetes mellitus (DM) carries an increased risk for cardiovascular complications. The brachial-ankle pulse wave velocity (baPWV) is an index for early atherosclerotic changes. Recently, the effect of ...
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Article
Mean platelet volume is negatively associated with bone mineral density in postmenopausal women
Osteoporosis (OP) has been associated with cardiovascular disease. More specifically, osteoporosis was found to be an independent predictor of cardiovascular mortality. Recent studies revealed that platelets p...
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Article
Open AccessA rare giant gastrointestinal stromal tumor of the stomach traversing the upper abdomen: a case report and literature review
We present the case of a 66-year-old woman with a huge gastrointestinal stromal tumor of the stomach that traversed her upper abdomen. The predominant abdominal sign was a huge, palpable mass, but there were n...
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Article
Knockdown of FoxM1 by siRNA interference decreases cell proliferation, induces cell cycle arrest and inhibits cell invasion in MHCC-97H cells in vitro
To investigate the effects of small interfering RNA (siRNA) knockdown of forkhead box M1 (FoxM1) on the proliferation and invasion capacities of human hepatocellular carcinoma MHCC-97H cells in vitro.