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  1. No Access

    Article

    The anticoordinate changes of pancreatic lipase and colipase activity to amylase activity induced by adrenalectomy in normal and diabetic rats

    The effect of adrenalectomy (Adx) on pancreatic lipase and colipase activities in normal, streptozotocin-induced diabetic, and obese Zucker rats was studied. It was found that Adx induced a rapid decrease in a...

    Rui-Dong Duan, Charlotte Erlanson-Albertsson in International journal of pancreatology (1990)

  2. No Access

    Article

    Age-Associated Alterations in Calcium Current and its Modulation in Cardiac Myocytes

    The calcium current is one of the most important components in cardiac excitation-contraction coupling. During aging, the magnitude of L-type Ca++ channel current (ICa,L) is significantly increased in parallel wi...

    Ying-Ying Zhou, Edward G. Lakatta, Dr Rui-** **ao in Drugs & Aging (1998)

  3. No Access

    Article

    Protein phosphatase 1α-mediated stimulation of apoptosis is associated with dephosphorylation of the retinoblastoma protein

    Protein phosphatase 1 (PP1) plays important roles in many different aspects of cellular activities including cell cycle control. One important function of PP1 is to activate the retinoblastoma protein pRB. Her...

    Rui-Hong Wang, Cathy W Y Liu, Vassilios I Avramis, Norbert Berndt in Oncogene (2001)

  4. No Access

    Article

    Expression and transactivating functions of the bZIP transcription factor GADD153 in mammary epithelial cells

    Heregulin-β1 (HRG), a combinatorial ligand for human epidermal growth factor receptor 3 (HER3) and HER4, is a regulatory polypeptide having distinct biological effects, such as growth stimulation, differentiat...

    Amjad H Talukder, Rui-An Wang, Rakesh Kumar in Oncogene (2002)

  5. No Access

    Chapter and Conference Paper

    Quantitative Determination of Bcl-2 Expression in AML Cell Lines and in Normal and Leukemic Progenitor Cell Compartments by Laser Scanning Cytometry: Comparison with Flow Cytometry and Western Blot

    Laser Scanning Cytometry (LSC) is a newly developed microscope-based and computerized system that directly analyzes up to 3- color fluorescence simultaneously from single cells attached to slides. It permits c...

    Rui-Yu Wang, D. Weidner, T. McQueen, J. McMannis, M. Korbling… in Acute Leukemias IX (2003)

  6. No Access

    Chapter and Conference Paper

    Leukemia Stem Cells with Efficient Drug Efflux in Acute Myeloid Leukemia

    Phenotypical dissection of the cellular heterogeneity in acute myeloid leukemia (AML) has recently dissolved this disease in a hierarchical organization of subpopulations with divergent proliferative potential...

    G. G. Wulf, Rui-Yu Wang, M. K. Brenner, M. Andreeff, M. A. Goodell in Acute Leukemias IX (2003)

  7. No Access

    Chapter and Conference Paper

    Reduced Level of Philadelphia Chromosome Positive (Ph+) Cells in Lineage Negative Side Population Bone Marrow Progenitor Cells from Patients with Chronic Myeloid Leukemia (CML)

    Recent reports have identified CD34neg normal hematopoietic stem cells from several species based on their Hoechst 33342 dual emission staining profile. Side population (SP) cells exclude Hoechst 33342 (Hoechstlo...

    D. A. Weidner, Rui-Yu Y. Wang, Shourong Zhao, L. Calvert, I. Kuehnle… in Acute Leukemias IX (2003)

  8. No Access

    Article

    Reduction in alkaline sphingomyelinase in colorectal tumorigenesis is not related to the APC gene mutation

    The sphingomyelin pathway is an important intracellular mechanism in regulating cell growth. The first step in this pathway is catalysed by sphingomyelinases. Alkaline sphingomyelinase is specifically located ...

    Erik Hertervig, Åke Nilsson, Mef Nilbert… in International Journal of Colorectal Disease (2003)

  9. No Access

    Article

    Purified intestinal alkaline sphingomyelinase inhibits proliferation without inducing apoptosis in HT-29 colon carcinoma cells

    Sphingomyelin (SM) hydrolysis by sphingomyelinase (SMase) has become an important signalling pathway, with the product ceramide implicated in regulation of cell growth, differentiation and apoptosis. Alkaline ...

    Erik Hertervig, Åke Nilsson, Yajun Cheng… in Journal of Cancer Research and Clinical On… (2003)

  10. No Access

    Article

    Differential proteomic analysis of human hepatocellular carcinoma cell line metastasis-associated proteins

    The comparative study of differentially expression of protein profiles of hepatocellular carcinoma cell lines with various metastasic potential and screening key molecules related to hepatocellular carcinoma ...

    Jie-Feng Cui, Yin-Kun Liu, Bo-Shen Pan… in Journal of Cancer Research and Clinical On… (2004)

  11. No Access

    Article

    Antisense Tcf inhibits the neoplastic growth of liver cancer cells

     T cell transcription factors are nuclear effectors of the Wnt signaling transduction pathway and play crucial roles in embryonic and malignant development. Our previous study showed increased expression level...

    Ying Jiang, **n-Da Zhou, Yin-Kun Liu… in Journal of Cancer Research and Clinical On… (2004)

  12. No Access

    Article

    Serum CYFRA 21-1 level reflects hepatocellular carcinoma metastasis: study in nude mice model and clinical patients

    Our previous proteomics study on human hepatocellular carcinoma (HCC) cell strains revealed that cytokeratin 19 (CK19) was expressed in cells with high metastasis potential; we further studied serum CK19 fragm...

    Yan Li, Zhao-You Tang, Bo Tian… in Journal of Cancer Research and Clinical On… (2006)

  13. No Access

    Article

    Clinical and genetic analysis for a Chinese family with hereditary fructose intolerance

    Hereditary fructose intolerance (HFI) is an inheritable disorder of fructose metabolism, inherited as an autosomal recessive disorder and caused by catalytic deficiency of aldolase B, which is critical for glu...

    Zhen-ni Chi, Jie Hong, Jun Yang, Hui-Jie Zhang, Meng Dai, Bin Cui, Yu Zhang… in Endocrine (2007)

  14. Article

    Open Access

    Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation

    Electroacupuncture (EA) has been reported to produce anti-edema and anti-hyperalgesia effects on inflammatory disease. However, the mechanisms are not clear. The present study investigated the biochemical mech...

    Aihui Li, Rui-**n Zhang, Yi Wang… in BMC Complementary and Alternative Medicine (2007)

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  15. No Access

    Article

    Ursolic acid inhibits the formation of aberrant crypt foci and affects colonic sphingomyelin hydrolyzing enzymes in azoxymethane-treated rats

    Ursolic acid (UA) is a pentacyclic triterpenoid, with anti-cancer and anti-inflammatory properties. Sphingomyelin (SM) hydrolysis generates lipid messengers regulating cell survival. Earlier studies showed tha...

    David Andersson, Yajun Cheng, Rui-Dong Duan in Journal of Cancer Research and Clinical On… (2008)

  16. No Access

    Article

    Influence of short- and long-term treadmill exercises on levels of ghrelin, obestatin and NPY in plasma and brain extraction of obese rats

    This study aims to clarify the effects of exercise on levels of appetite regulatory hormones in plasma and hypothalamus of obese rats. Diet-induced obese rats undergo short- (40 min) and long-term (40 min, 5 d...

    Jun Wang, Chen Chen, Rui-Yuan Wang in Endocrine (2008)

  17. No Access

    Article

    Intraocular pressure and endothelium cell counts after cataract surgery with chitosan and sodium hyaluronate (Healon GV): 3-Year follow-up results of a randomised clinical trial

    The purpose of this study was to evaluate the long-term effects of chitosan 0.1% and sodium hyaluronate 1.4% (Healon GV®; Advanced Medical Optics, Santa Ana, CA, USA) on intraocular pressure (IOP) and endothel...

    You Li, **-Wei Cheng, Rui-Li Wei, Chun-Lin Hou, Wen-Bin Wang… in Advances in Therapy (2008)

  18. No Access

    Article

    Comparison of free plasma metanephrines enzyme immunoassay with 131I-MIBG scan in diagnosis of pheochromocytoma

    Measurement of free plasma metanephrines (metanephrine and normetanephrine), usually performed by high-performance liquid chromatography with electrochemical detection (HPLC-ECD), has been recommended as the s...

    Yun-Chao Gao, Han-Kui Lu, Quan-Yong Luo, Li-Bo Chen… in Clinical and Experimental Medicine (2008)

  19. No Access

    Article

    Comparative proteomics and molecular mechanical analysis in CDA-II induced therapy of LCI-D20 hepatocellular carcinoma model

    To investigate the differential proteins and related molecular mechanism of CDA-II (cell differentiation agent-II) induced therapy on a human hepatocellular carcinoma model in nude mice with high metastatic po...

    Hui-zhi Fan, Hang Liu, Chen Zhang… in Journal of Cancer Research and Clinical On… (2009)

  20. No Access

    Article

    Expression of stathmin/op18 as a significant prognostic factor for cervical carcinoma patients

    Stathmin (Oncoprotein18), a ubiquitous and highly conserved 19-kDa cytosolic phosphoprotein, has been reported to play a critical role in mitosis and possibly other cellular processes, which is associated with...

    Wang **, Wang Rui, Lin Fang, Dong Ke… in Journal of Cancer Research and Clinical On… (2009)

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