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Article
Multisystem Inflammatory Syndrome in Children (MIS-C) Related to SARS-CoV-2 and 1-Year Follow-up
To study the demographics, clinical profile, management, outcome and 1-y follow-up of children with multisystem inflammatory syndrome in children (MIS-C).
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Chapter
Viral Hemorrhagic Fever
Viral hemorrhagic fever has caused a worrying number of deaths in recent years, leading to some outbreaks being declared by the World Health Organisation as an international emergency.
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Article
Relationship of postoperative vaginal anatomy and sexual function: a systematic review with meta-analysis
This was a planned secondary analysis of a systematic review that described sexual function outcomes following pelvic organ prolapse (POP) surgery. We aimed to describe the relationship of pre- and postoperati...
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Article
Open AccessA human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor–RPE interface
Mutations in CLN3 lead to photoreceptor cell loss in CLN3 disease, a lysosomal storage disorder characterized by childhood-onset vision loss, neurological impairment, and premature death. However, how CLN3 mutati...
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Article
Risk factors predicting the loss of functional independence after obliterative procedures for pelvic organ prolapse
To determine the risk factors associated with loss of functional independence after obliterative procedures for pelvic organ prolapse (POP).
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Article
Surgical interventions for posterior compartment prolapse and obstructed defecation symptoms: a systematic review with clinical practice recommendations
Several posterior compartment surgical approaches are used to address posterior vaginal wall prolapse and obstructed defecation. We aimed to compare outcomes for both conditions among different surgical approa...
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Article
Open AccessEnvironmental stress impairs photoreceptor outer segment (POS) phagocytosis and degradation and induces autofluorescent material accumulation in hiPSC-RPE cells
Retinal pigment epithelium (RPE) cell dysfunction is central to the pathogenesis of age-related macular degeneration (AMD), a leading cause of adult blindness. Aging, the single biggest risk factor for AMD dev...
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Article
Randomized controlled trial of silver-alloy-impregnated suprapubic catheters versus standard suprapubic catheters in assessing urinary tract infection rates in urogynecology patients
Catheter-associated urinary tract infections (UTI) are the most common health-care-related infections. We aimed to compare the UTI rate among women undergoing urogynecological procedures with a silver-alloy su...
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Article
Uterine-preserving surgeries for the repair of pelvic organ prolapse: a systematic review with meta-analysis and clinical practice guidelines
We aimed to systematically review the literature on pelvic organ prolapse (POP) surgery with uterine preservation (hysteropexy). We hypothesized that different hysteropexy surgeries would have similar POP outc...
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Article
Sitting versus standing makes a difference in musculoskeletal discomfort and postural load for surgeons performing vaginal surgery
We compared musculoskeletal discomfort and postural load among surgeons in sitting and standing positions during vaginal surgery.
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Chapter
Pluripotent Stem Cells to Model Degenerative Retinal Diseases: The RPE Perspective
Pluripotent stem cell technology, including human-induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs), has provided a suitable platform to investigate molecular and pathological alte...
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Article
Neuromodulation for Pelvic Pain and Sexual Dysfunction
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a common entity in patients with chronic pelvic pain. The diagnosis and treatment of this complex condition remains a challenge. This can lead to delayed...
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Article
Management of a vesicovaginal fistula using holmium laser ablation
The objective was to demonstrate a surgical technique for the management of a small vesicovaginal fistula (VVF) involving a combination of cystoscopic holmium laser ablation and vaginal repair.
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Article
Urogynecology digest
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Article
Open AccessExpression of epithelial calcium transport system in rat cochlea and vestibular labyrinth
The low luminal Ca2+ concentration of mammalian endolymph in the inner ear is required for normal hearing and balance. We recently reported the expression of mRNA for a Ca2+-absorptive transport system in primary...
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Article
Open AccessMacrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model
Pendred syndrome, an autosomal-recessive disorder characterized by deafness and goiter, is caused by a mutation of SLC26A4, which codes for the anion exchanger pendrin. We investigated the relationship between pe...
