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Article
Open AccessDeciphering spatial domains from spatial multi-omics with SpatialGlue
Advances in spatial omics technologies now allow multiple types of data to be acquired from the same tissue slice. To realize the full potential of such data, we need spatially informed methods for data integr...
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Article
Multimodal data integration using machine learning to predict the risk of clear cell renal cancer metastasis: a retrospective multicentre study
To develop and validate a predictive combined model for metastasis in patients with clear cell renal cell carcinoma (ccRCC) by integrating multimodal data.
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Article
Open AccessMeasurement of absolute branching fractions of \( {\textrm{D}}_{\textrm{s}}^{+} \) hadronic decays
Using e+e− collision data collected at the BESIII detector at center-of-mass energies between 4.128 and 4.226 GeV, corresponding to an integrated luminosity of 7.33 fb−1, we determine the absolute branching fract...
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Article
CircNSD1 promotes cardiac fibrosis through targeting the miR-429-3p/SULF1/Wnt/β-catenin signaling pathway
Cardiac fibrosis is a detrimental pathological process, which constitutes the key factor for adverse cardiac structural remodeling leading to heart failure and other critical conditions. Circular RNAs (circRNA...
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Article
Open AccessSearch for ∆S = 2 nonleptonic hyperon decays Ω− → Σ0π− and Ω− → nK−
Using (27.12 ± 0.14) × 108 ψ(3686) events collected by the BESIII detector at the center-of-mass energy of ...
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Article
Open AccessMeasurement of Born cross section of \( {e}^{+}{e}^{-}\to {\Sigma}^{+}{\overline{\Sigma}}^{-} \) at center-of-mass energies between 3.510 and 4.951 GeV
Using 24.1 fb−1 of e+e− collision data collected with the BESIII detector at the BEPCII collider, the Born cross sections and effective form factors of the ...
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Article
Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models
Autophagy impairment is a key factor in Alzheimer’s disease (AD) pathogenesis. TFEB (transcription factor EB) and TFE3 (transcription factor binding to IGHM enhancer 3) are nuclear transcription factors that r...
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Article
Open AccessAssociation between multiple-heavy-metal exposures and systemic immune inflammation in a middle-aged and elderly Chinese general population
Exposure to heavy metals alone or in combination can promote systemic inflammation. The aim of this study was to investigate potential associations between multiple plasma heavy metals and markers of systemic ...
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Article
Open AccessObservation of ψ(3686) → \( {\varOmega}^{-}{K}^{+}{\overline{\**}}^0 \) + c.c.
Using (27.12 ± 0.14) × 108 ψ(3686) events collected with the BESIII detector at BEPCII, the decay of ψ(3686) → ...
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Article
Cytogenetic analysis reveals a mechanism of compatibility in distant hybridization between tree peony and herbaceous peony
Cross-incompatibility is the major challenge in inter-sectional distant hybridization between tree peonies (Paeonia sect. Moutan) and herbaceous peonies (Paeonia sect. Paeonia). Most of the intersectional cross c...
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Article
Open AccessFirst-line camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and chemotherapy for advanced gastric cancer (SPACE): a phase 1 study
Patients with advanced gastric cancer typically face a grim prognosis. This phase 1a (dose escalation) and phase 1b (dose expansion) study investigated safety and efficacy of first-line camrelizumab plus apati...
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Article
Response to Discussion on “Thermal Effect Promotes Non-Darcian Flow in Heated Rock Fractures”
In a recent discussion by Rashida and Singh (Rock Mech Rock Eng, 2023) regarding our paper (Tan et al. Rock Mech Rock Eng 56:7599–7617, 2023) investigating the thermal effects on non-Darcian flow within heated...
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Open AccessThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia
In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However, the mechanisms underlying hyperthermia resistance are still poorly under...
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Article
Open AccessCorrection: Reduction of NgR in perforant path decreases amyloid-β peptide production and ameliorates synaptic and cognitive deficits in APP/PS1 mice
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Article
Open AccessMeasurement of the e+e− → \( {K}_S^0{K}_L^0 \) π0 cross sections from \( \sqrt{s} \) = 2.000 to 3.080 GeV
Based on e+e− collision data collected at center-of-mass energies from 2.000 to 3.080 GeV by the BESIII detector at the BEPCII collider, a partial wave analysis is performed for the process e+e− → ...
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Article
Open AccessSearch for the semi-muonic charmonium decay J/ψ → D−μ+νμ + c.c.
Using (10087 ± 44) × 106 J/ψ events collected with the BESIII detector at the BEPCII e+e− storage ring at the center-of-mass energy of ...
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Article
Open AccessPneumonia detection based on RSNA dataset and anchor-free deep learning detector
Pneumonia is a highly lethal disease, and research on its treatment and early screening tools has received extensive attention from researchers. Due to the maturity and cost reduction of chest X-ray technology...
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Open AccessMonitoring of urinary iodine concentration in naval pilots: should iodine be supplemented or limited at coastal stations?
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Article
Quantitative study of drilling-induced core damage through laboratory tests
Rock cores retrieved from deep rock masses may be permanently damaged on account of the stress release occurring during the drilling process. The quantification of core damage is important for accurate evaluat...
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Open AccessStudies of the decay \( {\textrm{D}}_{\textrm{s}}^{+}\to {\textrm{K}}^{+}{\textrm{K}}^{-}{\mu}^{+}{\nu}_{\mu } \)
The D s + → ...
