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Article
A Computational Framework for the Administration of 5-Aminovulinic Acid Before Glioblastoma Surgery
5-Aminolevulinic Acid (5-ALA) is the only fluorophore approved by the FDA as an intraoperative optical imaging agent for fluorescence-guided surgery in patients with glioblastoma. The dosing regimen is based o...
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Article
Mechanical properties and sustained drug release behavior of selective laser melted Ti6Al4V scaffolds modified using gentamicin loaded chitosan
Ti6Al4V scaffolds were successfully fabricated using selective laser melting followed by vacuum impregnation of gentamicin loaded chitosan. Microstructural observation revealed that Ti6Al4V scaffolds display p...
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Article
MFG model with a long-lived penalty at random jump times: application to demand side management for electricity contracts
We consider an energy system with n consumers who are linked by a Demand Side Management (DSM) contract, i.e. they agreed to diminish, at random times, their aggregated power consumption by a predefined volume du...
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Article
Open AccessEGFA-NAS: a neural architecture search method based on explosion gravitation field algorithm
Neural architecture search (NAS) is an extremely complex optimization task. Recently, population-based optimization algorithms, such as evolutionary algorithm, have been adopted as search strategies for design...
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Article
Molecular mechanism of Spatholobi Caulis treatment for cholangiocarcinoma based on network pharmacology, molecular docking, and molecular dynamics simulation
Cholangiocarcinoma (CCA) is a type of malignant tumor originating from the intrahepatic, periportal, or distal biliary system. The treatment means for CCA is limited, and its prognosis is poor. Spatholobi Caul...
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Article
Open AccessMonitoring of urinary iodine concentration in naval pilots: should iodine be supplemented or limited at coastal stations?
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Article
Open AccessCircNUP50 is a novel therapeutic target that promotes cisplatin resistance in ovarian cancer by modulating p53 ubiquitination
Most patients with ovarian cancer (OC) treated with platinum-based chemotherapy have a dismal prognosis owing to drug resistance. However, the regulatory mechanisms of circular RNA (circRNA) and p53 ubiquitina...
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Chapter and Conference Paper
A Novel Stable GO/PDA/CNT Double-Layer Low-Pressure Membrane for Humic Acid Removal
Based on the interface bonding function of polydopamine (PDA) coating, GO/PDA/CNT double-layer low-pressure membrane with stable mechanical properties was successfully loaded on the PES membrane by vacuum filt...
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Chapter and Conference Paper
Chatbot with Resilience: The Impact of Repair Strategies on Customer Satisfaction in Conversational Breakdowns
When chatbot is used in customer service, conversational breakdowns are common. Repairing from conversational breakdowns is a key step in service recovery. Drawing upon grounding in communication theory, this ...
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Chapter and Conference Paper
Research on Intelligent Clustering Scoring of English Text Based on XGBOOST Algorithm
In today's explosive growth of online text data, how to feature mine text data from a wide range of sources, cluster text data with similar features, and classify them according to their features has become a ...
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Article
Open AccessWhen chronic obstructive pulmonary disease meets small cell lung cancer: an unusual case report of rapid progression
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease and a risk factor for lung cancer. Small cell lung cancer is a neuroendocrine tumor with a high degree of malignancy and an overal...
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Article
Activated carbon with high mesopore ratio derived from waste Zanthoxylum bungeanum branches by KNO3-assisted H3PO4 staged activation for toluene adsorption
Waste Zanthoxylum bungeanum branches were used to prepare activated carbon adsorbents with high mesopore ratio by H3PO4 staged activation method with adding KNO3 additive. The prepared activated carbon adsorbents...
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Article
LncRNAs associated with vascular mimicry establish a novel molecular subtype and prognostic model for pancreatic cancer
Vascular mimicry (VM) epitomizes an innovative tumor angiogenesis pathway, potentially serving as an alternate conduit under the assumption of traditional tumor angiogenesis pathway inhibition. The role of VM ...
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Article
Open AccessMultidimensional quantitative phenotypic and molecular analysis reveals neomorphic behaviors of p53 missense mutants
Mutations in the TP53 tumor suppressor gene occur in >80% of the triple-negative or basal-like breast cancer. To test whether neomorphic functions of specific TP53 missense mutations contribute to phenotypic hete...
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Article
Open AccessHeat stress affects dairy cow health status through blood oxygen availability
Rises in global warming and extreme weather occurrence make the risk of heat stress (HS) induced by high ambient temperatures more likely in high-yielding dairy cows, resulting in low milk quality and yield. I...
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Article
Open AccessActionability classification of variants of unknown significance correlates with functional effect
Genomically-informed therapy requires consideration of the functional impact of genomic alterations on protein expression and/or function. However, a substantial number of variants are of unknown significance ...
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Article
Epidemiology of pediatric central nervous system tumors in Uyghur: experience from a single center
Retrospective analysis of clinical and epidemiological characteristics of central nervous system (CNS)tumors in Uyghur children from a single center in **njiang.
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Article
Open AccessClinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence
To investigate the influencing factors of the recurrence of IB1-IIA2 cervical squamous cell carcinoma after surgical treatment, and to explore the relationship between high-risk human papillomavirus (HR-HPV) i...
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Article
Kinetics Study on the Leaching of Copper from Calcification Roasting Copper Refining Slag Using Waste Acid
This research took the roasted products obtained by leaching copper (Cu) refining slag using waste acids and roasting leaching residues with calcium oxide (CaO) as raw materials and used oxidative leaching to ...
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Chapter and Conference Paper
Vacuum DC Surface Flashover Characteristic of Polyimide Under Electron Beam Irradiation
The DC flashover voltage of a solid dielectric in vacuum is much lower than the breakdown voltage of a vacuum gap or the solid dielectric itself of the same size. On the spacecraft, since the presence of energ...
