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Article
Open AccessModeling preeclampsia using human induced pluripotent stem cells
Preeclampsia (PE) is a pregnancy-specific hypertensive disorder, affecting up to 10% of pregnancies worldwide. The primary etiology is considered to be abnormal development and function of placental cells call...
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Article
Open AccessErratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development
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Article
Open AccessEstablishment of human iPSC-based models for the study and targeting of glioma initiating cells
Glioma tumour-initiating cells (GTICs) can originate upon the transformation of neural progenitor cells (NPCs). Studies on GTICs have focused on primary tumours from which GTICs could be isolated and the use o...
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Article
Open AccessStatistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development
The pervasive expression of circular RNA is a recently discovered feature of gene expression in highly diverged eukaryotes, but the functions of most circular RNAs are still unknown. Computational methods to d...
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Article
Open AccessMicrobes, metagenomes and marine mammals: enabling the next generation of scientist to enter the genomic era
The revolution in DNA sequencing technology continues unabated, and is affecting all aspects of the biological and medical sciences. The training and recruitment of the next generation of researchers who are a...
