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Article
Open AccessModeling preeclampsia using human induced pluripotent stem cells
Preeclampsia (PE) is a pregnancy-specific hypertensive disorder, affecting up to 10% of pregnancies worldwide. The primary etiology is considered to be abnormal development and function of placental cells call...
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Article
Open AccessErratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development
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Article
Open AccessEstablishment of human iPSC-based models for the study and targeting of glioma initiating cells
Glioma tumour-initiating cells (GTICs) can originate upon the transformation of neural progenitor cells (NPCs). Studies on GTICs have focused on primary tumours from which GTICs could be isolated and the use o...
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Article
Metabolic rescue in pluripotent cells from patients with mtDNA disease
Mutations in mitochondrial (mt)DNA are associated with severe disorders for which treatment is currently limited; this study shows that mtDNA mutations can be genetically corrected and normal metabolic functio...
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Article
Open AccessStatistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development
The pervasive expression of circular RNA is a recently discovered feature of gene expression in highly diverged eukaryotes, but the functions of most circular RNAs are still unknown. Computational methods to d...
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Chapter and Conference Paper
Retail Sales Clerk Evaluation Methods
A literature review serves as the basis for the construction of a consumer‐ oriented sales clerk evaluation methodology. Most current evaluations are from a managerial perspective and focus on store image or s...
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Article
Abnormalities in human pluripotent cells due to reprogramming mechanisms
Human pluripotent stem cells hold potential for regenerative medicine, but available cell types have significant limitations. Although embryonic stem cells (ES cells) from in vitro fertilized embryos (IVF ES cell...
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Article
Open AccessMicrobes, metagenomes and marine mammals: enabling the next generation of scientist to enter the genomic era
The revolution in DNA sequencing technology continues unabated, and is affecting all aspects of the biological and medical sciences. The training and recruitment of the next generation of researchers who are a...