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    Article

    Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

    Andre Franke and colleagues perform a genome-wide association study for the gut microbiome, examining the influence of host genetics on overall microbial variation and individual taxa. They find significant as...

    Jun Wang, Louise B Thingholm, Jurgita Skiecevičienė, Philipp Rausch in Nature Genetics (2016)

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    Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)

    Andre Franke and colleagues report results of a genome-wide association and replication study of ulcerative colitis. They identify two new regions of association at 7q22 and at 22q13 in IL17REL.

    Andre Franke, Tobias Balschun, Christian Sina, David Ellinghaus in Nature Genetics (2010)

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    Article

    A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

    We performed a genome-wide association study of 19,779 nonsynonymous SNPs in 735 individuals with Crohn disease and 368 controls. A total of 7,159 of these SNPs were informative. We followed up on all 72 SNPs ...

    Jochen Hampe, Andre Franke, Philip Rosenstiel, Andreas Till in Nature Genetics (2007)