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Article
Open AccessCellular transfection using rapid decrease in hydrostatic pressure
Of all methods exercised in modern molecular biology, modification of cellular properties through the introduction or removal of nucleic acids is one of the most fundamental. As such, several methods have aris...
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Reference Work Entry In depth
The Effect of Pressure on the Conformational Stability of DNA
Studies into the effect of hydrostatic pressure on the thermodynamic and kinetic properties of DNA provide insights into the interactions that stabilize the canonical and noncanonical DNA structures. Under mos...
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Living Reference Work Entry In depth
The Effect of Pressure on the Conformational Stability of DNA
Studies into the effect of hydrostatic pressure on the thermodynamic and kinetic properties of DNA provide insights into the interactions that stabilize the canonical and noncanonical DNA structures. Under mos...
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Living Reference Work Entry In depth
Volumetric Properties of Biomolecular Systems
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Article
Binding of a dimeric manganese porphyrin to serum albumin: towards a gadolinium-free blood-pool T 1 MRI contrast agent
As the first clinically approved gadolinium-based blood-pool MRI contrast agent, gadofosveset was designed to bind to human serum albumin (HSA) reversibly, extending the circulation time in the bloodstream. Th...