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  1. Article

    Human mtDNA hypervariable regions, HVR I and II, hint at deep common maternal founder and subsequent maternal gene flow in Indian population groups

    We have analysed the hypervariable regions (HVR I and II) of human mitochondrial DNA (mtDNA) in individuals from Uttar Pradesh (UP), Bihar (BI) and Punjab (PUNJ), belonging to the Indo-European linguistic grou...

    Swarkar Sharma, Anjana Saha, Ekta Rai, Audesh Bhat… in Journal of Human Genetics (2005)

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    Functional IFNG polymorphism in intron 1 in association with an increased risk to promote sporadic breast cancer

    Interferon (IFN)-γ is an important Th1 cytokine, which plays a role in immune surveillance and anti-tumor activity. A case-control study involving 54 sporadic breast cancer patients and 144 healthy controls wa...

    Anjana Saha, Ashish Dhir, Anand Ranjan, Vibhuti Gupta, Narendra Bairwa… in Immunogenetics (2005)

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    TLR2 Arg677Trp polymorphism in leprosy: revisited

    We investigated the Toll-like receptor 2 (TLR2) Arg677Trp polymorphism, associated with lepromatous leprosy in the Korean population and shown to abrogate TLR2-mediated signalling in response to mycobacterial ...

    Dheeraj Malhotra, Vineet Relhan, B. S. N. Reddy, Ramesh Bamezai in Human Genetics (2005)

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    Gel-Based Nonradioactive Single-Strand Conformational Polymorphism and Mutation Detection

    Single-strand conformation polymorphism (SSCP) for screening mutations/single-nucleotide polymorphisms (SNPs) is a simple, cost-effective technique, saving an expensive exercise of sequencing each and every PC...

    Vibhuti Gupta, Reetakshi Arora, Anand Ranjan… in Molecular Toxicology Protocols (2005)

  5. Article

    Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow

    Four binary polymorphisms and four multiallelic short tandem repeat (STR) loci from the nonrecombining region of the human Y-chromosome were typed in different Indian population groups from Uttar Pradeh (UP), ...

    Anjana Saha, Swarkar Sharma, Audesh Bhat, Awadesh Pandit… in Journal of Human Genetics (2005)

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    Microsatellite Instability

    The DNA mismatch repair (MMR) pathway plays a prominent role in the correction of errors made during DNA replication and genetic recombination and in the repair of small deletions and loops in DNA. Mismatched ...

    Anjana Saha, Narendra K. Bairwa, Ramesh Bamezai in Molecular Toxicology Protocols (2005)

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    Comparison of Established Cell Lines at Different Passages by Karyotype and Comparative Genomic Hybridization

    Two established cancer cell lines, MCF-7 and Ishikawa, were both obtained directly from a cell repository and through another laboratory. The karyotypes from the two MCF-7 cell lines had up to 83 chromosomes a...

    Sharon L. Wenger, Jamie R. Senft, Linda M. Sargent, Ramesh Bamezai… in Bioscience Reports (2004)