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  1. Article

    The Role of RNA Epigenetic Modification in Normal and Malignant Hematopoiesis

    RNA epigenetic modifications have been identified as novel, dynamic regulators of gene expression, with important impacts on stem cell fate decisions. Here, we examine the functions of RNA modifications, with ...

    Radovan Vasic, Yimeng Gao, Chengyang Liu, Stephanie Halene in Current Stem Cell Reports (2020)

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    SRSF2 mutations drive oncogenesis by activating a global program of aberrant alternative splicing in hematopoietic cells

    Recurrent mutations in the splicing factor SRSF2 are associated with poor clinical outcomes in myelodysplastic syndromes (MDS). Their high frequency suggests these mutations drive oncogenesis, yet the molecular e...

    Yang Liang, Toma Tebaldi, Kai Rejeski, Poorval Joshi, Giovanni Stefani… in Leukemia (2018)