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  1. No Access

    Article

    Bile acid-induced “Minority MOMP” promotes esophageal carcinogenesis while maintaining apoptotic resistance via Mcl-1

    Barrett’s esophagus (BE) is associated with reflux and is implicated the development of esophageal adenocarcinoma (EAC). Apoptosis induces cell death through mitochondrial outer membrane permeabilization (MOMP...

    Yuan Xu, Deborah R. Surman, Laurence Diggs, Sichuan **, Shaojian Gao… in Oncogene (2020)

  2. No Access

    Article

    Trends in Major Gastrectomy for Cancer: Frequency and Outcomes

    Declining incidence of gastric cancer in the USA has presumably resulted in lower rates of major gastrectomy for cancer. The impact on perioperative outcomes remains undefined. The aims of this study were to c...

    Eric M. Groh, Noorie Hyun, David Check, Theo Heller… in Journal of Gastrointestinal Surgery (2019)

  3. Article

    Open Access

    Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy

    Esophageal cancers accounted for nearly 16,000 deaths in 2016. The number of patients with esophageal cancers increases every year. Neoadjuvant chemoradiotherapy (nCRT) prior to esophagectomy is a standard tre...

    R. Taylor Ripley, Deborah R. Surman, Laurence P. Diggs… in BMC Gastroenterology (2018)

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  4. Article

    Open Access

    Regional Chemotherapy in Locally Advanced Pancreatic Cancer: RECLAP Trial

    Pancreatic cancer is the fourth leading cause of cancer death in the United States. Surgery offers the only chance for cure. However, less than twenty percent of patients are considered operative candidates at...

    Jeremy L Davis, Prakash Pandalai, R Taylor Ripley, Russell C Langan… in Trials (2011)

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