-
Article
Effects of growth hormone in short children after renal transplantation
From 1991 to 1993, 90 children having received a kidney graft with a post-transplantation period of at least 12 months were included in a prospective study carried out in 18 French pediatric centers. After in...
-
Article
Divergence of VP7 genes of G1 rotaviruses isolated from infants vaccinated with reassortant rhesus rotaviruses
A large placebo-controlled efficacy trial of the rhesus tetravalent (RRV-TV) and serotype G1 monovalent (RRV-S1) rotavirus vaccines was conducted in 1991–1992 at 24 sites across the United States. Protection w...
-
Chapter
Plasma Growth Hormone-Binding Protein and Liver Receptor in Thalassemic Patients
Children with thalassemia major often present with growth failure, the mechanism of which is not clear. They are not GH deficient but their plasma insulin-like growth factor I (IGFI) activity is markedly reduced ...
-
Chapter and Conference Paper
Growth Hormone Treatment of Children with Intrauterine Growth Retardation
The follow-up studies of infants born with intrauterine growth retardation (IUGR) have shown that some of them are not doing well with reference to postnatal growth (Davies 1981; Fancourt et al. 1976; Fitzhard...
-
Article
Predictive factors for the effect of gonadotrophin releasing hormone analogue therapy on the height of girls with idiopathic central precocious puberty
The factors influencing the final height of central precocious puberty patients treated with gonadotrophin releasing hormone (GnRH) analogues remain a critical issue. This study compares the predicted final he...
-
Chapter
Kinder- und Adoleszentengynäkologie / EDV
Ein 9jähriges Mädchen wurde in die senologische Sprechstunde überwiesen wegen einer seit 3 Monaten bestehenden Schwellung und lividen Verfärbung der linken Mamille, welche trotz lokaler antibiotischer, antimyk...
-
Article
Plasma growth hormone-binding activity is low in uraemic children
Plasma growth hormone-binding protein (GH-BP) activity was evaluated in two groups of prepubertal children with chronic renal failure (CRF) who had been treated with recombinant human GH (rhGH). Group 1 consis...
-
Article
Height of normal pituitary gland as a function of age evaluated by magnetic resonance imaging in children
MR anatomy of hypothalamo-hypophyseal axis is well established. However data about pituitary gland height (PGH) in children are sparse. A retrospective study was therefore performed in 60 children (30 boys and...
-
Article
Polygraphic sleep patterns and growth hormone secretion in children after cranial irradiation
The effects of radiotherapy on subsequent growth hormone (GH) secretion and sleep organization was studied by simultaneous evaluation of spontaneous sleep-related GH secretion (SSRGHS), arginine-insulin tolera...
-
Article
Growth and endocrine disorders in optic glioma
Hypothalamo-pituitary function in children with optic glioma may be impaired by the tumour itself and by the high cranial radiation doses used in treatment. This study evaluates the effect of optic glioma and ...
-
Chapter
Should All Girls with Central Precocious Puberty be Treated by LHRH Analogue?
In central precocious puberty (CPP), the premature increase in sex steroid secretion induces an acceleration of the growth rate and an excessive bone age progression which may lead to adult short stature. In g...
-
Chapter
Adrenal Steroid Metabolism Disorders
Congenital adrenal hyperplasia is a classic metabolic disease. It encompasses almost the totality of defects of the adrenal steroidogenesis. Recent advances have been due to the finding that the 21-hydroxylase...
-
Chapter and Conference Paper
Cytokinesis in Animal Cells
The organizers of this meeting probably placed cytokinesis first because it has long been an object of curiosity, speculation and investigation and because it appears to be a relatively simple event. It has be...
-
Article
Effect of Somatomedin-C/Insulin-Like Growth Factor I and Growth Hormone on Cultured Growth Plate and Articular Chondrocytes
ABSTRACT: To determine whether growth hormone has a direct effect on skeletal tissues not mediated by somatomedins, and to better define the role of somatomedin-C/ insulin-like growth factor I (Sm-C/IGF-I) in ...
-
Chapter and Conference Paper
Growth hormone secretory dysfunction after hypothalamic and pituitary irradiation
External cranial radiation is a major therapeutic tool in the treatment of various malignant diseases in children. As growth retardation has become a significant complication of this therapy, there have been q...
-
Article
MRI of hypothalamic hamartomas in children
Eight cases of hypothalamic hamartomas (HH) diagnosed in children by clinical, biological and CT studies have been explored by MRI and compared with a control group of twenty children without hypothalamohypoph...
-
Article
53 SUSTAINED GROWTH IN SPITE OF RADIATION INDUCED GHD OCCURS ONLY AFTER LOW HYPOTHALAMO-PITUITARY DOSE
Normal growth, despite GHD, has been reported after cranial radiation (CR) for leukemia (ALL). In order to analyze the characteristicsof the patients with GH peak <5 ng/ml after AITT, 2 groups were investigate...
-
Article
140 INFLUENCE OF LOW OR HIGH ESTROGEN ACTIVITY ON GROWTH AND PLASMA Sm-C and GIRIS WITH CENTRAL PRECOCIOUS PUBERTY (CPP)
The effect of low or high E2 levels on Sm-C and growth have not been evaluated in children over prolonged periods. In this study we investigated the relationship between plasma E2 and Sm-C levels and pubertal ...
-
Article
71 CALORIC SUPPLEMENTATION INDUCES GROWTH ACCELERATION WITHOUT Sm-C CHANGES IN A LARON TYPE DWARF
Circulating Sm–C reflects protein synthesis and the ability to stimulate skeletal growth in close relationship with caloric intake. The occurence of spontaneous chronic undereating in a boy with Laron type dwa...
-
Article
6 TESTICULAR IRRADIATION (TI) FOR ACUTE LYMPHOBLASTIC LEUKEMIA (ALL): LONG TERM FOLLOW-UP OF LEYDIG CELL FUNCTION AND PUBERTAL DEVELOPMENT
Leydig cell insufficiency is a frequent complication of bilateral TI with 24 gy (NEJM 1983). To describe the long term follow-up and the testosterone (T) deficiency we studied, with an interval time since TI >...
