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Article
Qu’en est-il du sentiment de guérison chez le jeune adulte atteint d’un cancer dans l’enfance ou dans l’adolescence ?
Une étude du sentiment de guérison à distance d’un cancer traité avant l’âge de 15 ans a été conduite, au cours d’entretiens semi-directifs menés par la psychologue, chez 25 jeunes gens de 18 à 31 ans médicale...
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Article
From childhood to adulthood: long-term outcome of medulloblastoma patients. The Institut Curie experience (1980–2000)
Medulloblastoma patients treated at the Institute Curie between 1980 and 2000 were reviewed. Only patients whose primary treatment included craniospinal radiation were considered. Surviving patients were ident...
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Article
An Experimental Investigation into the Acoustic Characteristics of Fluid-filled Porous Structures—A Simplified Model of the Human Skull Cancellous Structure
In nature, shape and structure evolve from the struggle for better performance. Often, biological structures combine multiple beneficial properties, making research into mimicking them very complex. Presented ...
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Article
Peripheral blood stem cell collection in 24 low-weight infants: experience of a single centre
Peripheral blood stem cells (PBSC) harvest may be difficult in young children. Extracorporeal separator line priming by red blood cells is usually required to improve haemodynamic tolerance and efficacy of col...
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Article
Open AccessThe LMCE5 unselected cohort of 25 children consecutively diagnosed with untreated stage 4 neuroblastoma over 1 year at diagnosis
The Lyon-Marseille-Curie-Est (LMCE) of France cooperative group has previously reported successive series of unselected stage four children older than 1 year at diagnosis with metastatic neuroblastoma (LMCE 1 ...
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Article
Hepatic regenerating nodules: a mimic of recurrent cancer in children
Background. Pseudometastatic lesions of the liver may be discovered incidentally in children previously treated for malignant tumour.¶Objective. To describe the radiological pattern of these lesions and to analy...
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Article
Open AccessSecond malignant neoplasms after a first cancer in childhood: temporal pattern of risk according to type of treatment
The variation in the risk of solid second malignant neoplasms (SMN) with time since first cancer during childhood has been previously reported. However, no study has been performed that controls for the distri...
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Article
A limited-sampling method for evaluation of the area under the curve of ultrafilterable carboplatin in children
Carboplatin is a widely used cytotoxic agent in numerous solid tumors of children. Since there is a large degree of interpatient variability in the area under the curve of free carboplatin for a given dose of ...
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Article
Growth and endocrine disorders in optic glioma
Hypothalamo-pituitary function in children with optic glioma may be impaired by the tumour itself and by the high cranial radiation doses used in treatment. This study evaluates the effect of optic glioma and ...
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Article
Initial chemotherapy including ifosfamide in the management of Ewing's sarcoma: preliminary results A protocol of the French Pediatric Oncology Society (SFOP)
Phase II studies using ifosfamide both alone and combined with vindesine and cisplatin have shown the effectiveness of this drug in patients with Ewing's sarcoma (ES) who had relapsed during VAC (vincristine, ...
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Article
53 SUSTAINED GROWTH IN SPITE OF RADIATION INDUCED GHD OCCURS ONLY AFTER LOW HYPOTHALAMO-PITUITARY DOSE
Normal growth, despite GHD, has been reported after cranial radiation (CR) for leukemia (ALL). In order to analyze the characteristicsof the patients with GH peak <5 ng/ml after AITT, 2 groups were investigate...
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Article
Histological, cytological and immunological analyses are complementary for the detection of neuroblastoma cells in bone marrow
On 80 occasions 4 iliac biopsy trephines and 4 iliac aspirations were performed in 37 children with neuroblastoma at various stages of the disease. In 38 of these procedures, tumour cells were detected. In 24%...
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Article
Transplantability in nude mice of embryonic and other childhood tumours
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Article
Echographic aspects of hepatic metastases of nephroblastomas
We report a retrospective study of 293 cases of nephroblastoma treated at the Gustave Roussy Institute (I. G. R), from 1971 to 1980, and 39 similar cases treated at the Curie Institute (I. C), from June 1977 t...
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Article
Normal bone maturation in GH and somatomedin (SM) deficient children with pituitary irradiation for retinoblastoma
Growth hormone deficiency is a frequent consequence of external cranial radiation. Retinoblastoma is a particular situation with radiation ( 3500 rads) performed before age of 4 yr. 30 prepubertal children wer...
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Radiochemotherapy of Postoperative Minimal Residual Disease in Neuroblastoma
Two-year survival of neuroblastoma patients has not been substantially improved in the last 20 years, either in localized and regional disease or in metastatic tumors (Tab. 1) [1, 16, 19, 23]. As in other tumo...
