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Article
Open AccessTranscriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines
Variation in the expression level and activity of genes involved in drug disposition and action (‘pharmacogenes’) can affect drug response and toxicity, especially when in tissues of pharmacological importance...
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Article
Effects of dietary saturated fat on LDL subclasses and apolipoprotein CIII in men
Small dense low-density lipoprotein (LDL) particles and apolipoprotein (apo) CIII are risk factors for cardiovascular disease (CVD) that can be modulated by diet, but there is little information regarding the ...
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Article
Clinical implications of pharmacogenomics of statin treatment
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Article
Monoclonal antibodies and immobilized antibodies
Antibodies in both their free and immobilized state have been the object of considerable industrial and academic interest. A variety of methods are used for preparing and immobilizing antibodies. Applications ...
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Article
Intercorrelations among plasma high density lipoprotein, obesity and triglycerides in a normal population
The interrelationships among fatness measures, plasma triglycerides and high density lipoproteins (HDL) were examined in 131 normal adult subjects: 38 men aged 27–46, 40 men aged 47–66, 29 women aged 27–46 and...
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Article
Effects of estrogens and progestins on high density lipoproteins
High density lipoprotein (HDL) levels are known to be higher in women than in men, and to increase with estrogen use. To assess the effects of estrogens on HDL subspecies, analytic ultracentrifuge measurements...