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Article
Abnormally large, heavy brain with a decreased number of apoptotic cells in CYP7B1 knockout mice
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Article
Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain
This study reports on the spatiotemporal dynamics of the expression of estrogen receptors (ERs) in the mouse central nervous system (CNS) during the early postnatal and the peripubertal period. At postnatal da...
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Chapter
Molecular Analysis of H23 Epithelial Tumor Antigen - Differentially Spliced Full Length cDNAs and Gene
The isolation and characterization of the complementary DNAs (cDNAs) and gene which code for an epithelial tumor antigen (H23-ETA), aberrantly expressed in human breast tumor tissue, are described here. A dive...
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Article
Expression of Human Anti-Hemophilic Factor IX in the Milk of Transgenic Sheep
Transgenic livestock may prove useful for the large scale production of valuable proteins. By targeting expression to the mammary gland these proteins could be harvested from milk. To this end, we have designe...
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Chapter and Conference Paper
Vaccinia Recombinants Expressing Foreign Antigens: Antiviral and Antitumor Immunity
Virus infection elicits a variety of symptoms. In man infection can provoke immunosuppression [e.g., human immunodeficiency virus (HIV)], behavioral changes (e.g., rabies), or neoplastic transformation [e.g., ...
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Chapter
New Generation of Rabies Vaccine
Rabies is a disease of major significance to human and veterinary medicine. Derivatives of the vaccine developed by Pasteur and associates 100 years ago (1885) are still in use in many parts of the world. Duri...
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Article
Tumour prevention and rejection with recombinant vaccinia
Tumour-specific antigens (TSA; ref. 1) have been exploited in the diagnosis2 and imaging3 of human cancer and anti-TSA antibodies have therapeutic potential4. Vaccination with TSA5–8 or anti-idiotypic (TSA) anti...
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Article
Oral vaccination of the fox against rabies using a live recombinant vaccinia virus
Rabies, a viral disease affecting all warm-blooded animals, is prevalent in most parts of the world1, where it propagates amongst wild animals, particularly the fox and dog. The public health and economic consequ...
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Article
Novel DNA sequence representations (reply)
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Chapter and Conference Paper
Genetically Engineered Rabies Subunit Vaccines
The attempt to control the proliferation of rabies virus remains a major preoccupation of health authorities worldwide. Effective vaccines based upon inactivated rabies virus have been developed, however the c...
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Article
Expression of rabies virus glycoprotein from a recombinant vaccinia virus
Rabies is one of the oldest diseases known to man, but its successful control has remained elusive. Although effective vaccines of tissue culture origin against rabies do exist1, such preparations are expensive. ...
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Article
Machine-readable DNA sequences
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Article
The firA gene, a locus involved in the expression of rifampicin resistance in Escherichia coli
The firA gene probably codes for an essential component of the transcription machinery in E. coli. Bacterial proteins coded by λfirA transducing phages have been examined after infection of a UV-irradiated λ lyso...
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Article
The firA gene, a locus involved in the expression of rifampicin resistance in Escherichia coli
The firA200 mutation of E. coli not only renders RNA synthesis thermosensitive but also eliminates the high-level resistance to rifampicin associated with certain mutations in the β subunit of the RNA polymerase....
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Article
Nomenclature and location of bacterial mutations modifying the frequency of lysogenization of E. coli by lambdoid phages