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  1. No Access

    Article

    Abnormally large, heavy brain with a decreased number of apoptotic cells in CYP7B1 knockout mice

    N Sugiyama, S Andersson, R Lathe, X Fan, P Alonso-Magdalena in Molecular Psychiatry (2009)

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    Article

    Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain

    This study reports on the spatiotemporal dynamics of the expression of estrogen receptors (ERs) in the mouse central nervous system (CNS) during the early postnatal and the peripubertal period. At postnatal da...

    N Sugiyama, S Andersson, R Lathe, X Fan, P Alonso-Magdalena in Molecular Psychiatry (2009)

  3. No Access

    Chapter

    Molecular Analysis of H23 Epithelial Tumor Antigen - Differentially Spliced Full Length cDNAs and Gene

    The isolation and characterization of the complementary DNAs (cDNAs) and gene which code for an epithelial tumor antigen (H23-ETA), aberrantly expressed in human breast tumor tissue, are described here. A dive...

    D. H. Wreschner, I. Tsarfaty, M. Hareuveni, J. Zaretsky in Breast Epithelial Antigens (1991)

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    Article

    Expression of Human Anti-Hemophilic Factor IX in the Milk of Transgenic Sheep

    Transgenic livestock may prove useful for the large scale production of valuable proteins. By targeting expression to the mammary gland these proteins could be harvested from milk. To this end, we have designe...

    A. J. Clark, H. Bessos, J. O. Bishop, P. Brown, S. Harris, R. Lathe in Bio/Technology (1989)

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    Chapter and Conference Paper

    Vaccinia Recombinants Expressing Foreign Antigens: Antiviral and Antitumor Immunity

    Virus infection elicits a variety of symptoms. In man infection can provoke immunosuppression [e.g., human immunodeficiency virus (HIV)], behavioral changes (e.g., rabies), or neoplastic transformation [e.g., ...

    M. P. Kieny, R. Lathe in Progress in Vaccinology (1989)

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    Chapter

    New Generation of Rabies Vaccine

    Rabies is a disease of major significance to human and veterinary medicine. Derivatives of the vaccine developed by Pasteur and associates 100 years ago (1885) are still in use in many parts of the world. Duri...

    T. J. Wiktor, M. P. Kieny, R. Lathe in New Vaccines and Chemotherapy (1988)

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    Article

    Tumour prevention and rejection with recombinant vaccinia

    Tumour-specific antigens (TSA; ref. 1) have been exploited in the diagnosis2 and imaging3 of human cancer and anti-TSA antibodies have therapeutic potential4. Vaccination with TSA5–8 or anti-idiotypic (TSA) anti...

    R. Lathe, M. P. Kieny, P. Gerlinger, P. Clertant, I. Guizani, F. Cuzin in Nature (1987)

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    Article

    Oral vaccination of the fox against rabies using a live recombinant vaccinia virus

    Rabies, a viral disease affecting all warm-blooded animals, is prevalent in most parts of the world1, where it propagates amongst wild animals, particularly the fox and dog. The public health and economic consequ...

    J. Blancou, M. P. Kieny, R. Lathe, J. P. Lecocq, P. P. Pastore, J. P. Soulebot in Nature (1986)

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    Article

    Novel DNA sequence representations (reply)

    R. LATHE, R. FINDLAY in Nature (1985)

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    Chapter and Conference Paper

    Genetically Engineered Rabies Subunit Vaccines

    The attempt to control the proliferation of rabies virus remains a major preoccupation of health authorities worldwide. Effective vaccines based upon inactivated rabies virus have been developed, however the c...

    J. P. Lecocq, M. P. Kieny, P. Curtis, R. Lathe in Rabies in the Tropics (1985)

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    Article

    Expression of rabies virus glycoprotein from a recombinant vaccinia virus

    Rabies is one of the oldest diseases known to man, but its successful control has remained elusive. Although effective vaccines of tissue culture origin against rabies do exist1, such preparations are expensive. ...

    M. P. Kieny, R. Lathe, R. Drillien, D. Spehner, S. Skory, D. Schmitt, T. Wiktor in Nature (1984)

  12. Article

    Machine-readable DNA sequences

    R. LATHE, R. FINDLAY in Nature (1984)

  13. No Access

    Article

    The firA gene, a locus involved in the expression of rifampicin resistance in Escherichia coli

    The firA gene probably codes for an essential component of the transcription machinery in E. coli. Bacterial proteins coded by λfirA transducing phages have been examined after infection of a UV-irradiated λ lyso...

    R. Lathe, J. P. Lecocq in Molecular and General Genetics MGG (1977)

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    Article

    The firA gene, a locus involved in the expression of rifampicin resistance in Escherichia coli

    The firA200 mutation of E. coli not only renders RNA synthesis thermosensitive but also eliminates the high-level resistance to rifampicin associated with certain mutations in the β subunit of the RNA polymerase....

    R. Lathe, J. P. Lecocq, A. Resibois in Molecular and General Genetics MGG (1977)

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    Article

    Nomenclature and location of bacterial mutations modifying the frequency of lysogenization of E. coli by lambdoid phages

    J. P. Lecocq, C. Dambly, R. Lathe, C. Babinet in Molecular and General Genetics MGG (1976)