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Article
Magenstumpfkarzinom: Häufigkeit, Therapie, Komplikationen und Prognose
Magenstumpfkarzinome entstehen im Restmagen nach partieller Gastrektomie. Während die Häufigkeit des Magenkarzinoms abnimmt, bleibt die Inzidenz des Magenstumpfkarzinoms aufgrund einer langen Latenzzeit stabil...
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Article
Salvage-Chirurgie bei Ösophaguskarzinomen
Bei Ösophaguskarzinomen werden nach definitiver Radio(chemo)therapie bei Progression oder Rezidiv oder auf Patientenwunsch immer häufiger Salvage-Ösophagektomien in Tumorboards diskutiert.
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Article
Massive Knochendestruktion nach vorderer Kreuzbandplastik
Knocheninfektionen mit Pilzen nach vorderer Kreuzbandplastik stellen eine sehr seltene Komplikation dar. Sie wurden jedoch in der Vergangenheit außerhalb Europas schon mehrfach beschrieben. Hierbei handelt es ...
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Chapter
Diagnostics particuliers
Déf.: La cytogénétique et l’hybridation fluorescente in situ (FISH) sont des méthodes utilisées pour déceler les anomalies chromosomiques clonales des cellules malignes → essentielles au diagnostic, ...
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Article
Comparison of five prognostic scoring systems, the French–American–British (FAB) and World Health Organization (WHO) classifications in patients with myelodysplastic syndromes: results of a single-center analysis
We retrospectively studied 89 consecutive patients diagnosed with primary myelodysplastic syndrome (MDS) over a period of 10 years to (1) identify prognostic factors for overall survival (OS) and leukemia-free...
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Article
Prognosis of older patients with acute myeloid leukemia receiving either induction or noncurative treatment: a single-center retrospective study
Since few studies focus on prognostic factors in unselected elderly acute myeloid leukemia (AML) patients, a retrospective analysis of 138 consecutive patients aged >55 years (median age: 67, range: 56–89) wit...
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Chapter and Conference Paper
Single-Center Retrospective Analysis of Prognosis of 138 Patients Older than 55 Years with Acute Myeloid Leukemia
Background. A retrospective analysis was performed on 138 consecutive patients aged >55 years (median age 67, range 56–89) with AML diagnosed at a single center over an 8-year period (1/1991 to 1...
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Article
Rapid achievement of complete donor chimerism and low regimen-related toxicity after reduced conditioning with fludarabine, carmustine, melphalan and allogeneic transplantation
between august 1998 and july 1999, 21 patients received a novel protocol of reduced conditioning with fludarabine, carmustine and melphalan (fbm) followed by matched-related allogeneic peripheral blood stem ce...
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Article
Adoptive immunotherapy for relapsed multiple myeloma after allogeneic bone marrow transplantation (BMT): evidence for a graft-versus-myeloma effect
Adoptive immunotherapy with donor-derived buffy coat cells for relapsed hematological malignancies after allogeneic BMT is an established and highly effective treatment. We report a patient who relapsed on day...
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Article
Detection of chromosome 11q23 involving translocations by pulsed field gel electrophoresis
Translocations involving chromosome band 11q23 are associated with acute lymphocytic and myelomonocytic leukemias with poor clinical prognosis. Pulsed-field gel electrophoresis (PFGE) was used to characterize ...
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Article
Karyotype analyses of 20 human glioma cell lines
Human malignant gliomas are frequently associated with loss of gonosomes and chromosomes 13, 17, and 22. Their progression from anaplastic glioma to glioblastoma is marked by additional loss of chromosome 10. ...
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Article
Transfer of the 1BL/1RS wheat-rye-translocation from hexaploid bread wheat to tetraploid durum wheat
The present study describes a cytological stable alien chromosome translocation in tetraploid durum wheat. By crossing the hexaploid 1BL/1RS wheat-rye translocation line “Veery” to the tetraploid durum wheat c...