45 Result(s)

Article

Aktuelle therapeutische Ansätze bei ZNS-Tumoren

Pädiatrische Hirntumoren umfassen biologisch, klinisch und prognostisch ein äußerst heterogenes Spektrum von Entitäten.

S. Rutkowski, M. Mynarek, T. Milde, S. Dietzsch, R. D. Kortmann in Der Onkologe (2021)

Article

Nimotuzumab and radiotherapy for treatment of newly diagnosed diffuse intrinsic pontine glioma (DIPG): a phase III clinical study

Diffuse intrinsic pontine glioma (DIPG) is a devastating cancer of childhood and adolescence.

G. Fleischhack, M. Massimino, M. Warmuth-Metz, E. Khuhlaeva… in Journal of Neuro-Oncology (2019)

Living Reference Work Entry In depth

Radiation Therapy in Craniopharyngioma

Craniopharyngioma are rare intracranial, perisellar tumors of adamantinomatous or papillary subtype. Alhough “benign” in nature they might lead to devastating deficits or death in children or adults. After sur...

C. Seidel, J. Meixensberger, R. -D. Kortmann in Radiation Oncology

Article

Analysis of frequency of deep white matter metastasis on cerebral MRI

Supratentorial white matter is an important part of the brain and a major site of detrimental effects after whole brain radiotherapy (WBRT). It is not known if prevalence of metastases in white matter justifie...

C. Seidel, P. Hambsch, K. Hering, A. Bresch, S. Rohde… in Journal of Neuro-Oncology (2015)

Article

Treatment of recurrent primitive neuroectodermal tumors (PNET) in children and adolescents with high-dose chemotherapy (HDC) and stem cell support: results of the HITREZ 97 multicentre trial

Early studies with high-dose chemotherapy for treatment of relapsed cerebral PNET had shown modest efficacy but considerable toxicity. The HIT97 national trial tested a nonrandomized but stratified relapse pro...

U. Bode, M. Zimmermann, O. Moser, S. Rutkowski… in Journal of Neuro-Oncology (2014)

Article

Craniospinal irradiation with concurrent temozolomide for primary metastatic pediatric high-grade or diffuse intrinsic pontine gliomas

High-grade (HGG) and diffuse intrinsic pontine gliomas (DIPG) with primary metastatic spread are extremely rare and have a dismal prognosis. Analogous to simultaneous radiochemotherapy in non-metastatic HGG an...

K. Müller, A. Schlamann, M. Guckenberger, M. Warmuth-Metz… in Strahlentherapie und Onkologie (2014)

Article

Die Chemotherapiesequenz vor oder nach Strahlentherapie hat keinen Einfluss auf das Überleben der Kinder mit Hochrisiko-Medulloblastomen

R.-D. Kortmann in Strahlentherapie und Onkologie (2014)

Article

Radiotherapy in pediatric pilocytic astrocytomas

We evaluated clinical outcomes in the subset of patients who underwent radiotherapy (RT) due to progressive pilocytic astrocytoma within the Multicenter Treatment Study for Children and Adolescents with a Low ...

K. Müller M.D., A. Gnekow, F. Falkenstein… in Strahlentherapie und Onkologie (2013)

Article

Craniospinal irradiation with concurrent temozolomide and nimotuzumab in a child with primary metastatic diffuse intrinsic pontine glioma

Primary metastatic diffuse intrinsic pontine glioma (DIPG) is relatively rare and associated with a dismal prognosis. Combining craniospinal irradiation (CSI) with concurrent temozolomide and nimotuzumab thera...

K. Müller, A. Schlamann, C. Seidel, M. Warmuth-Metz… in Strahlentherapie und Onkologie (2013)

Article

Meningioma as second malignant neoplasm after oncological treatment during childhood

A total of 38 patients (18 female/20 male) with childhood meningioma were recruited from the German registry HIT-Endo (1989–2009). In 5 cases meningioma occurred as second malignant neoplasm (SMN). Histologies...

H.L. Müller MD, U. Gebhardt, M. Warmuth-Metz, T. Pietsch… in Strahlentherapie und Onkologie (2012)

Article

Strahlentherapie bei Hirntumoren

Die moderne Strahlentherapie bietet durch eine Vielzahl technischer Weiterentwicklungen die Möglichkeit, eine hohe präzise Strahlendosis auf exakt definierte Zielvolumina zu applizieren und umgebende Risikostr...

Prof. Dr. A.-L. Grosu, R.-D. Kortmann in Der Nervenarzt (2010)

Article

Quality of care and emotional support from the inpatient cancer patient’s perspective

Patient satisfaction and emotional support are crucial elements of cancer care. Little is known, however, about which areas of care are important from the patient’s perspective and the roles emotional distress...

S. Singer, H. Götze, C. Möbius, H. Witzigmann… in Langenbeck's Archives of Surgery (2009)

Article

Kraniopharyngeom im Kindes- und Jugendalter

Kraniopharyngeome sind dysontogenetische Mittellinienfehlbildungen mit raumforderndem Charakter. Bei einer Inzidenz von 0,5–2/10⁶/Jahr werden 30–50% der Fälle im Kindes- und Jugendalter manifest. Bei häufig lange...

Prof. Dr. H.L. Müller, U. Gebhardt, R.-D. Kortmann… in Monatsschrift Kinderheilkunde (2008)

Article

Hohe Rückfallraten nach Kraniopharyngeom im Kindes- und Jugendalter

In der Querschnittsstudie HIT-ENDO wurden 258 Kinder und Jugendliche mit Kraniopharyngeom hinsichtlich Therapie und Langzeitprognose analysiert. Die prospektive Beobachtungsstudie KRANIOPHARYNGEOM 2000 untersu...

Prof. Dr. H.L. Müller, U. Gehardt… in Monatsschrift Kinderheilkunde Zeitschrift … (2008)

Chapter

Radiotherapy for Tumors of the Anterior Visual Pathway

G. Becker, R. -D. Kortmann, H. Wilhelm in Clinical Neuro-Ophthalmology (2007)