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Article
Open AccessEvaluation of antiviral activity of Ocimum sanctum and Acacia arabica leaves extracts against H9N2 virus using embryonated chicken egg model
In the view of endemic avian influenza H9N2 infection in poultry, its zoonotic potential and emergence of antiviral resistance, two herbal plants, Ocimum sanctum and Acacia arabica, which are easily available thr...
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Article
A rare penetrant TIMP3 mutation confers relatively late onset choroidal neovascularisation which can mimic age-related macular degeneration
To perform a genotype–phenotype correlation for three patients heterozygous for a missense mutation in the tissue inhibitor of metalloproteinase 3 (TIMP3) gene.
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Article
Somatic mutational landscape of AML with inv(16) or t(8;21) identifies patterns of clonal evolution in relapse leukemia
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Article
Cross-sectional study indicates nearly a quarter of sheep population in Karnataka state of India is infected with ovine herpesvirus 2
In a cross-sectional study, prevalence of ovine herpesvirus 2 (family: Herpesviridae, subfamily: Gammaherpesvirinae, genus Macavirus and species: Ovine herpesvirus 2) infection was estim...
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Article
Genetic and antigenic analysis of H5N1 viruses for selection of HA-donor virus for vaccine strains
Genetic and antigenic analysis of H5N1 viruses, isolated in India during a period from year 2006 to 2010, was carried out for selection of the potential H5-HA (haemagglutinin) gene donor virus for develo** a...
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Article
Bovine immunodeficiency virus: a lentiviral infection
The bovine immunodeficiency virus (BIV) is a lentivirus which is known to infect cattle worldwide. Though serological and genomic evidence of BIV in cattle has been found throughout the world, isolation of the...
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Article
Open AccessOR13-001 Loss-of-function mutations in CECR1, encoding adenosine deaminase 2 (ADA2), cause recurrent fevers and early onset strokes
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Article
The effect of opioids and their antagonists on the nocifensive response of Caenorhabditis elegans to noxious thermal stimuli
Opiates modulate nociception in vertebrates. This has also been demonstrated in a number of invertebrate models. Herein, the effect of the opiate morphine and opioid neuropeptides Endomorphin 1 and 2 on the th...
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Chapter and Conference Paper
Drug delivery by nanoparticles — facing the obstacles
There are numerous concepts of nanoparticle mediated drug delivery. The major advantage will be the option of targeted drug delivery to specific target cells thus avoiding high systemic loads of potentially to...
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Article
Energy harvesting MEMS device based on thin film piezoelectric cantilevers
A thin film lead zirconate titanate Pb(Zr,Ti)O3 (PZT), energy harvesting MEMS device is developed to enable self-supportive sensors for in-service integrity monitoring of large social and environmental infrastruc...
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Article
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome
We report here the identification of a gene associated with the hyperparathyroidism–jaw tumor (HPT–JT) syndrome. A single locus associated with HPT–JT (HRPT2) was previously mapped to chromosomal region 1q25–q32....
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Article
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1
Although prostate cancer is the most common non-cutaneous malignancy diagnosed in men in the United States1,2, little is known about inherited factors that influence its genetic predisposition3,4,5. Here we repor...
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Article
Use of experimentally constructed haplotypes in gene map** studies of hereditary cancers
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Article
Use of experimentally constructed haplotypes in gene map** studies of hereditary cancers
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Article
Elongated SNRs: Possible New Jet Sources
We summarise the properties of selected supernova remnants (SNRs) which have elongated envelopes that could house relativistic jets. We present MOPRA and SEST millimeter observations of these objects, showing ...
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Chapter and Conference Paper
Elongated SNRs: Possible New Jet Sources
We summarise the properties of selected supernova remnants (SNRs) which have elongated envelopes that could house relativistic jets. We present MOPRA and SEST millimeter observations of these objects, showing ...
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Article
Status of epidermal growth factor receptors family in hormone-dependent carcinomas of the breast and prostate with reference to serum lipids and lipoproteins
There are numerous growing evidences of resemblance between carcinomas of the breast and prostate. A total of 45 cases of these two hormone-dependent cancers along with appropriate controls were subjected for ...
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Article
Forced expression of the leukemia-associated gene EVI1 in ES cells: a model for myeloid leukemia with 3q26 rearrangements
Chromosome band 3q26 is the locus of two genes, MDS1/EVI1 and EVI1. The proteins encoded by these genes are nuclear factors each containing two separate DNA-binding zinc finger domains. The proteins are identical...
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Article
Placenta Percreta Invading the Bladder Causing Exsanguinating Hemorrhage
We report a case of placenta percreta invading the urinary bladder that presented as gross hematuria. The patient had normal cystoscopic findings initially and other radiological investigations were reported ...
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Article
MDS1/EVI1 enhances TGF-β1 signaling and strengthens its growth-inhibitory effect, but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-β1
MDS1/EVI1, located on chromosome 3 band q26, encodes a zinc-finger DNA-binding transcription activator not detected in normal hematopoietic cells but expressed in several normal tissues. MDS1/EVI1 is inappropriat...