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O-GlcNAcylation is involved in the transcriptional activity of EWS-FLI1 in Ewing's sarcoma
The oncogene EWS-FLI1 encodes a chimeric transcription factor expressed in Ewing's sarcoma family tumors (ESFTs). EWS-FLI1 target gene expression is thought to drive ESFT pathogenesis and, therefore, inhibition o...