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  1. Article

    Open Access

    Clinical phenotypes and outcomes associated with SARS-CoV-2 Omicron sublineage JN.1 in critically ill COVID-19 patients: a prospective, multicenter cohort study in France, November 2022 to January 2024

    A notable increase in severe cases of COVID-19, with significant hospitalizations due to the emergence and spread of JN.1 was observed worldwide in late 2023 and early 2024. However, no clinical data are avail...

    Nicolas de Prost, Etienne Audureau, Antoine Guillon in Annals of Intensive Care (2024)

  2. Article

    Open Access

    Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys

    CD4+ T-cell depletion is a hallmark of HIV infection, leading to impairment of cellular immunity and opportunistic infections, but its contribution to SIV/HIV-associated gut dysfunction is unknown. Chronically SI...

    Quentin Le Hingrat, Paola Sette, Cuiling Xu, Andrew R. Rahmberg in Nature Communications (2023)

  3. Article

    Open Access

    SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients

    Data on SARS-CoV-2 load in lower respiratory tract (LRT) are scarce. Our objectives were to describe the viral shedding and the viral load in LRT and to determine their association with mortality in critically...

    Niccolò Buetti, Paul-Henri Wicky, Quentin Le Hingrat, Stéphane Ruckly in Critical Care (2020)

  4. Article

    Open Access

    Seroprevalence and risk factors for HIV, HCV, HBV and syphilis among blood donors in Mali

    HIV, HBV and HCV remain a global public health concern especially in Africa. Prevalence of these infections is changing and identification of risk factors associated with each infection in Mali is needed to im...

    Aude Jary, Sidi Dienta, Valentin Leducq, Quentin Le Hingrat in BMC Infectious Diseases (2019)

  5. Article

    Open Access

    Characterization update of HIV-1 M subtypes diversity and proposal for subtypes A and D sub-subtypes reclassification

    The large and constantly evolving HIV-1 pandemic has led to an increasingly complex diversity. Because of some taxonomic difficulties among the most diverse HIV-1 subtypes, and taking advantage of the large am...

    Nathalie Désiré, Lorenzo Cerutti, Quentin Le Hingrat, Marine Perrier in Retrovirology (2018)

  6. Article

    Open Access

    Illegal gold miners in French Guiana: a neglected population with poor health

    In French Guiana, a French overseas territory in South America, 6 to 10 thousands undocumented persons work illegally in gold mining sites in the Amazonian forest. Precarious life conditions lead to poor healt...

    Maylis Douine, Emilie Mosnier, Quentin Le Hingrat in BMC Public Health (2017)